EFFECT OF RAW CAMEL MILK IN TYPE 2 DIABETES ANIMAL MODELS AND PATIENTS: TEN MONTHS RANDOMISED STUDY

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	EFFECT OF RAW CAMEL MILK IN TYPE 2 DIABETES ANIMAL MODELS AND PATIENTS: TEN MONTHS RANDOMISED STUDY
	Wang, SY; Liang, JP; Song, NN; Shao, WJ; Heng, H; Wang, SY (reprint author), Gansu Agr Univ, Dept Anim Med, Lanzhou 730070, Peoples R China.
刊名	JOURNAL OF CAMEL PRACTICE AND RESEARCH
	2009-06
卷号	16 期号:1 页码:107-113
关键词	Animals models camel milk glycaemia control Rosiglitazone Maleate Type 2 diabetes
ISSN号	0971-6777
文献子类	Article
英文摘要	The efficacy of camel milk consumption as an adjunct to routine diabetes management in maintaining long-term glycaemia control in type 2 diabetes was assessed by 32 type 2 diabetes animal models and 12 patients. Thirty-two obese diabetic rats were divided into 4 groups according to method of random digits table. After 14 weeks treatment, it was observed that no significant variance compared Rosiglitazone Maleate group, Rosiglitazone Maleate+camel milk group and camel milk group with normal group. In blood glucose, blood triglycerides, blood total cholesterol, and plasma insulin there were a statistically significant change compared with diabetes group. Rosiglitazone Maleate group and Rosiglitazone Maleate+camel milk group showed significant variance in blood triglycerides (0.68+/-0.19 vs. 0.51+/-0.11 p<0.05), plasma insulin (43.52+/-18.93 vs. 26.49+/-5.60 p<0.05). Rosiglitazone Maleate+calnel milk group was more similar to normal group. Rosiglitazone Maleate+camel milk group had better treatment of type 2 diabetes animal models than Rosiglitazone Maleate group. Throughout the duration of the study, 6 randomly assigned patients underwent routine diabetes management and 6 randomly assigned patients additionally undertook daily consumption of raw camel milk (500 ml/day). In both groups, the dose of potential Rosiglitazone Maleate administration was adjusted to maintain a euglycaemic. In the group receiving camel milk, there was a significant increase in body weight (74.6+/-5.2 to 78.3+/-3.4; p<0.05) and a significant reduction in mean blood sugar (123+/-19.8 to 94.2+/-14.3; p<0.001), plasma insulin (19.76+/-2.3 to 6.2+/-0.56; p<0.001), dose of drug (4.67+/-0.91 to 1.67+/-1.3; p<0.001), blood triglycerides (1.83+/- 0.38 to 1.42+/-0.94; p<0.001), blood total cholesterol (7.7+/-1.53 to 6.1+/-0.91; p<0.001) compared to the values at the initiation of the study. Based on the results, camel milk consumption may be considered as a useful prevention and adjunct to potential Rosiglitazone Maleate administration in the management of type 2 diabetes.
学科主题	Veterinary Sciences
出版地	BIKANER
项目编号	Gansu Hualong Agricultural Development Corporation
语种	英语
WOS记录号	WOS:000272063900019
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/121426]
专题	基础医学院_期刊论文
通讯作者	Wang, SY (reprint author), Gansu Agr Univ, Dept Anim Med, Lanzhou 730070, Peoples R China.
推荐引用方式 GB/T 7714	Wang, SY,Liang, JP,Song, NN,et al. EFFECT OF RAW CAMEL MILK IN TYPE 2 DIABETES ANIMAL MODELS AND PATIENTS: TEN MONTHS RANDOMISED STUDY[J]. JOURNAL OF CAMEL PRACTICE AND RESEARCH,2009,16(1):107-113.
APA	Wang, SY,Liang, JP,Song, NN,Shao, WJ,Heng, H,&Wang, SY .(2009).EFFECT OF RAW CAMEL MILK IN TYPE 2 DIABETES ANIMAL MODELS AND PATIENTS: TEN MONTHS RANDOMISED STUDY.JOURNAL OF CAMEL PRACTICE AND RESEARCH,16(1),107-113.
MLA	Wang, SY,et al."EFFECT OF RAW CAMEL MILK IN TYPE 2 DIABETES ANIMAL MODELS AND PATIENTS: TEN MONTHS RANDOMISED STUDY".JOURNAL OF CAMEL PRACTICE AND RESEARCH 16.1(2009):107-113.