Biodegradable electrospun fibers for drug delivery

	Biodegradable electrospun fibers for drug delivery
	Zeng J ; Xu XY ; Chen XS ; Liang QZ ; Bian XC ; Yang LX ; Jing XB
刊名	journal of controlled release
	2003
卷号	92 期号:3 页码:227-231
关键词	POLYMER TEMPLATE FIBERS DIAMETER FIBERS NANOFIBERS JETS
ISSN号	0168-3659
通讯作者	jing xb
中文摘要	the influences of surfactants and medical drugs on the diameter size and uniformity of electrospun poly(l-lactic acid) (plla) fibers were examined by adding various surfactants (cationic, anionic, and nonionic) and typical drugs into the plla solution. significant diameter reduction and uniformity improvement were observed. it was shown that the drugs were capsulated inside of the fibers and the drug release in the presence of proteinase k followed nearly zero-order kinetics due to the degradation of the plla fibers. such ultrafine fiber mats containing drugs may find clinical applications in the future.
收录类别	SCI
语种	英语
WOS记录号	WOS:000186260200001
公开日期	2010-09-13
内容类型	期刊论文
源URL	[http://202.98.16.49/handle/322003/17867]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Zeng J,Xu XY,Chen XS,et al. Biodegradable electrospun fibers for drug delivery[J]. journal of controlled release,2003,92(3):227-231.
APA	Zeng J.,Xu XY.,Chen XS.,Liang QZ.,Bian XC.,...&Jing XB.(2003).Biodegradable electrospun fibers for drug delivery.journal of controlled release,92(3),227-231.
MLA	Zeng J,et al."Biodegradable electrospun fibers for drug delivery".journal of controlled release 92.3(2003):227-231.