QuEChERS Purification Combined with Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry for Simultaneous Quantification of 25 Mycotoxins in Cereals

doi:10.3390/toxins8120375

	QuEChERS Purification Combined with Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry for Simultaneous Quantification of 25 Mycotoxins in Cereals
	Sun, Juan 1,2; Li, Weixi 1,2; Zhang, Yan 1,2; Hu, Xuexu 1,2; Wu, Li 1,2; Wang, Bujun 1,2
刊名	TOXINS
	2016
卷号	8 期号:12 页码:-
关键词	ultrahigh performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) QuEChERS mycotoxin cereals
ISSN号	2072-6651
DOI	10.3390/toxins8120375
通讯作者	Sun, Juan
英文摘要	A method based on the QuEChERS (quick, easy, cheap, effective, rugged, and safe) purification combined with ultrahigh performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS), was optimized for the simultaneous quantification of 25 mycotoxins in cereals. Samples were extracted with a solution containing 80% acetonitrile and 0.1% formic acid, and purified with QuEChERS before being separated by a C18 column. The mass spectrometry was conducted by using positive electrospray ionization (ESI+) and multiple reaction monitoring (MRM) models. The method gave good linear relations with regression coefficients ranging from 0.9950 to 0.9999. The detection limits ranged from 0.03 to 15.0 mu g.kg(-1), and the average recovery at three different concentrations ranged from 60.2% to 115.8%, with relative standard deviations (RSD%) varying from 0.7% to 19.6% for the 25 mycotoxins. The method is simple, rapid, accurate, and an improvement compared with the existing methods published so far.
学科主题	Toxicology
语种	英语
出版者	MDPI AG
WOS记录号	WOS:000393580000009
内容类型	期刊论文
源URL	[http://111.203.20.206/handle/2HMLN22E/105277]
专题	作物科学研究所_谷物检测中心
作者单位	1.Chinese Acad Agr Sci, Inst Crop Sci, Beijing 100081, Peoples R China 2.Minist Agr, Lab Qual & Safety Risk Assessment Cereal Prod Bei, Beijing 100081, Peoples R China
推荐引用方式 GB/T 7714	Sun, Juan,Li, Weixi,Zhang, Yan,et al. QuEChERS Purification Combined with Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry for Simultaneous Quantification of 25 Mycotoxins in Cereals[J]. TOXINS,2016,8(12):-.
APA	Sun, Juan,Li, Weixi,Zhang, Yan,Hu, Xuexu,Wu, Li,&Wang, Bujun.(2016).QuEChERS Purification Combined with Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry for Simultaneous Quantification of 25 Mycotoxins in Cereals.TOXINS,8(12),-.
MLA	Sun, Juan,et al."QuEChERS Purification Combined with Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry for Simultaneous Quantification of 25 Mycotoxins in Cereals".TOXINS 8.12(2016):-.