Genome-wide association mapping reveals novel sources of resistance to northern corn leaf blight in maize

doi:10.1186/s12870-015-0589-z

	Genome-wide association mapping reveals novel sources of resistance to northern corn leaf blight in maize
	Ding, Junqiang 1; Ali, Farhan 1; Chen, Gengshen 1; Li, Huihui 2; Mahuku, George 3; Yang, Ning 1; Narro, Luis 3; Magorokosho, Cosmos 3; Makumbi, Dan 3; Yan, Jianbing 1
刊名	BMC PLANT BIOLOGY
	2015
卷号	15 页码:-
ISSN号	1471-2229
DOI	10.1186/s12870-015-0589-z
通讯作者	Ding, Junqiang
英文摘要	Background: Northern corn leaf blight (NCLB) caused by Exserohilum turcicum is a destructive disease in maize. Using host resistance to minimize the detrimental effects of NCLB on maize productivity is the most cost-effective and appealing disease management strategy. However, this requires the identification and use of stable resistance genes that are effective across different environments.Results: We evaluated a diverse maize population comprised of 999 inbred lines across different environments for resistance to NCLB. To identify genomic regions associated with NCLB resistance in maize, a genome-wide association analysis was conducted using 56,110 single-nucleotide polymorphism markers. Single-marker and haplotype-based associations, as well as Anderson-Darling tests, identified alleles significantly associated with NCLB resistance. The single-marker and haplotype-based association mappings identified twelve and ten loci (genes), respectively, that were significantly associated with resistance to NCLB. Additionally, by dividing the population into three subgroups and performing Anderson-Darling tests, eighty one genes were detected, and twelve of them were related to plant defense. Identical defense genes were identified using the three analyses.Conclusion: An association panel including 999 diverse lines was evaluated for resistance to NCLB in multiple environments, and a large number of resistant lines were identified and can be used as reliable resistance resource in maize breeding program. Genome-wide association study reveals that NCLB resistance is a complex trait which is under the control of many minor genes with relatively low effects. Pyramiding these genes in the same background is likely to result in stable resistance to NCLB.
学科主题	Plant Sciences
语种	英语
出版者	BIOMED CENTRAL LTD
WOS记录号	WOS:000360047600001
内容类型	期刊论文
源URL	[http://111.203.20.206/handle/2HMLN22E/4675]
专题	作物科学研究所_分子生物学系
作者单位	1.Huazhong Agr Univ, Natl Key Lab Crop Genet Improvement, Wuhan 430070, Peoples R China 2.Chinese Acad Agr Sci, Inst Crop Sci, Beijing 100081, Peoples R China 3.Int Maize & Wheat Improvement Ctr CIMMYT, Global Maize Program, Mexico City 06600, DF, Mexico
推荐引用方式 GB/T 7714	Ding, Junqiang,Ali, Farhan,Chen, Gengshen,et al. Genome-wide association mapping reveals novel sources of resistance to northern corn leaf blight in maize[J]. BMC PLANT BIOLOGY,2015,15:-.
APA	Ding, Junqiang.,Ali, Farhan.,Chen, Gengshen.,Li, Huihui.,Mahuku, George.,...&Yan, Jianbing.(2015).Genome-wide association mapping reveals novel sources of resistance to northern corn leaf blight in maize.BMC PLANT BIOLOGY,15,-.
MLA	Ding, Junqiang,et al."Genome-wide association mapping reveals novel sources of resistance to northern corn leaf blight in maize".BMC PLANT BIOLOGY 15(2015):-.