[Ru(bpy)2dppz]2+ electrochemiluminescence switch and its applications for DNA interaction study and label-free ATP aptasensor

	[Ru(bpy)2dppz]2+ electrochemiluminescence switch and its applications for DNA interaction study and label-free ATP aptasensor
	Hu LZ ; Bian Z ; Li HJ ; Han S ; Yuan YL ; Gao LX ; Xu GB
刊名	analytical chemistry
	2009
卷号	81 期号:23 页码:9807-9811
ISSN号	1520-6882
中文摘要	[ru(bpy)2dppz]2+ electrochemiluminescence (ecl) was studied, and it was used to investigate dna interaction and develop a label-free atp aptasensor for the first time. ecl of [ru(bpy)2dppz]2+ is negligible in aqueous solution, and increases approximately 1000 times when [ru(bpy)2dppz]2+ intercalates into the nucleic acid structure. the ecl switch behavior of [ru(bpy)2dppz]2+ is ascribed to the intercalation that shields the phenazine nitrogens from the solvent and results in a luminescent excited state. the ecl switch by dna was applied to investigate the interaction of [ru(bpy)2dppz]2+ with herring sperm dna. the calculated equilibrium constant (k) is 1.35 x 10(6) m(-1), and the calculated binding-site size (s) is 0.88 base pair, which is consistent with the reported values.
收录类别	SCI
语种	英语
公开日期	2010-05-04 ; 2011-06-09
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/11403]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Hu LZ,Bian Z,Li HJ,et al. [Ru(bpy)2dppz]2+ electrochemiluminescence switch and its applications for DNA interaction study and label-free ATP aptasensor[J]. analytical chemistry,2009,81(23):9807-9811.
APA	Hu LZ.,Bian Z.,Li HJ.,Han S.,Yuan YL.,...&Xu GB.(2009).[Ru(bpy)2dppz]2+ electrochemiluminescence switch and its applications for DNA interaction study and label-free ATP aptasensor.analytical chemistry,81(23),9807-9811.
MLA	Hu LZ,et al."[Ru(bpy)2dppz]2+ electrochemiluminescence switch and its applications for DNA interaction study and label-free ATP aptasensor".analytical chemistry 81.23(2009):9807-9811.