Quantum Dot-Based Molecularly Imprinted Polymers on Three-Dimensional Origami Paper Microfluidic Chip for Fluorescence Detection of Phycocyanin

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 中科院海岸带环境过程与生态修复重点实验室

	Quantum Dot-Based Molecularly Imprinted Polymers on Three-Dimensional Origami Paper Microfluidic Chip for Fluorescence Detection of Phycocyanin
	Li, Bowei1 ; Zhang, Zhong 1,2; Qi, Ji 1,4; Zhou, Na 1; Qin, Song1 ; Choo, Jaebum 3; Chen, Lingxin1,4
刊名	ACS SENSORS
	2017-02-01
卷号	2 期号:2 页码:243-250
关键词	paper-based microfluidic devices molecularly imprinted polymers (MIPs) quantum dot phycocyanin fluorescence
ISSN号	2379-3694
通讯作者	Chen, LX (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China. ; Choo, J (reprint author), Hanyang Univ, Dept Bionano Engn, Ansan 426791, South Korea. ; Chen, LX (reprint author), Yantai Univ, Sch Environm & Mat Engn, Yantai 264005, Peoples R China. jbchoo@hanyang.ac.kr ; lxchen@yic.ac.cn
产权排序	[Li, Bowei; Zhang, Zhong; Qi, Ji; Zhou, Na; Qin, Song; Chen, Lingxin] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China; [Zhang, Zhong] Shaanxi Normal Univ, Coll Food Engn & Nutr Sci, Xian 710119, Peoples R China; [Choo, Jaebum] Hanyang Univ, Dept Bionano Engn, Ansan 426791, South Korea; [Qi, Ji; Chen, Lingxin] Yantai Univ, Sch Environm & Mat Engn, Yantai 264005, Peoples R China
英文摘要	In this work, we developed a novel strategy using fluorescent quantum dots (QDs) combined with molecularly imprinted polymers (MIPs) on three-dimensional (3D) origami paper-based microfluidic devices for specific recognition and sensitive detection of phycocyanin. This method can realize the liquid phase of QDs@MIPs being transferred to the solid-phase paper base and achieve easy portability for the analysis. Under optimal conditions, we successfully demonstrated the proposed paper@QDs@MIP5 3D microfluidic chip for the sensitive and selective detection of phycocyanin protein target in a simple and robust manner. Our results revealed that the method exhibited a dynamic response to phycocyanin in the range of 10-50 mg/L with a limit of detection of 2 mg/L. Importantly, this device could provide quantitative information very conveniently and show great potential to be further extended to the detection of other proteins or biomarkers for environmental and food safety research.
学科主题	Chemistry; Science & Technology - Other Topics
研究领域[WOS]	Chemistry ; Science & Technology - Other Topics
关键词[WOS]	METHYLAMINO-L-ALANINE ; NEUROTOXIC AMINO-ACID ; CYANOBACTERIAL TOXINS ; SIGNAL AMPLIFICATION ; DEVICE ; MICROSPHERES ; COOCCURRENCE ; RECOGNITION ; POPULATIONS ; BIOASSAYS
收录类别	SCI
原文出处	10.1021/acssensors.6b00664
语种	英语
WOS记录号	WOS:000395047000009
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/22072]
专题	烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 2.Shaanxi Normal Univ, Coll Food Engn & Nutr Sci, Xian 710119, Peoples R China 3.Hanyang Univ, Dept Bionano Engn, Ansan 426791, South Korea 4.Yantai Univ, Sch Environm & Mat Engn, Yantai 264005, Peoples R China
推荐引用方式 GB/T 7714	Li, Bowei,Zhang, Zhong,Qi, Ji,et al. Quantum Dot-Based Molecularly Imprinted Polymers on Three-Dimensional Origami Paper Microfluidic Chip for Fluorescence Detection of Phycocyanin[J]. ACS SENSORS,2017,2(2):243-250.
APA	Li, Bowei.,Zhang, Zhong.,Qi, Ji.,Zhou, Na.,Qin, Song.,...&Chen, Lingxin.(2017).Quantum Dot-Based Molecularly Imprinted Polymers on Three-Dimensional Origami Paper Microfluidic Chip for Fluorescence Detection of Phycocyanin.ACS SENSORS,2(2),243-250.
MLA	Li, Bowei,et al."Quantum Dot-Based Molecularly Imprinted Polymers on Three-Dimensional Origami Paper Microfluidic Chip for Fluorescence Detection of Phycocyanin".ACS SENSORS 2.2(2017):243-250.