Cytotoxic rearranged angucycline glycosides from deep sea-derived Streptomyces lusitanus SCSIO LR32

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	Cytotoxic rearranged angucycline glycosides from deep sea-derived Streptomyces lusitanus SCSIO LR32
	Zhu, XC; Duan, YW; Cui, ZM; Wang, Z; Li, ZX; Zhang, Y; Ju, JH; Huang, HB
刊名	JOURNAL OF ANTIBIOTICS
	2017
卷号	70 期号:7 页码:819-822
通讯作者	huanghb@scsio.ac.cn
中文摘要	Two new rearranged linear angucycline glycosides, designated grincamycins G and H (1 and 2), together with three known congers P-1894B (vineomycin A(1), 3), saquayamycin B (4) and vineomycin B-2 (5), were obtained from marine-derived actinomycete Streptomyces lusitanus SCSIO LR32. The structures of 1 and 2 were elucidated by MS, 1D and 2D NMR techniques. Compounds 2-5 showed significant inhibitory effect on Jurkat T-cell proliferation with IC50 values of 3.0, 0.011, 0.037 and 0.3 mu M, respectively.
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/16303]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
推荐引用方式 GB/T 7714	Zhu, XC,Duan, YW,Cui, ZM,et al. Cytotoxic rearranged angucycline glycosides from deep sea-derived Streptomyces lusitanus SCSIO LR32[J]. JOURNAL OF ANTIBIOTICS,2017,70(7):819-822.
APA	Zhu, XC.,Duan, YW.,Cui, ZM.,Wang, Z.,Li, ZX.,...&Huang, HB.(2017).Cytotoxic rearranged angucycline glycosides from deep sea-derived Streptomyces lusitanus SCSIO LR32.JOURNAL OF ANTIBIOTICS,70(7),819-822.
MLA	Zhu, XC,et al."Cytotoxic rearranged angucycline glycosides from deep sea-derived Streptomyces lusitanus SCSIO LR32".JOURNAL OF ANTIBIOTICS 70.7(2017):819-822.