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	Study on biochemical materials with development of hollow and paclitaxel-loaded bubbles for ultrasound controlled drug release
	Wu, Shi Chao ; Yang, Xiang Rui ; Hou, Zhen Qing ; Jiang, Qian ; Wang, Yan Ge ; Hou ZQ(侯振清)
	2013
关键词	Emulsification Lecithin Nanotechnology
英文摘要	Conference Name:2013 2nd International Conference on Function Materials and Nanotechnology, FMN2013. Conference Address: Nanchang, China. Time:July 13, 2013 - July 14, 2013.; Wuhan institute of technology; Beijing Material Research Center; International Material Research Society, Hong Kong; We report a new type of biochemical material multifunctional paclitaxel-loaded poly lactide-lecithin (PLA-lecithin) microbubbles which has been developed with a method of ultrasonic double emulsion solvent evaporation (UDES) combined with lyophilization. Bubbles were characterized to be hollow, well dispersed andwith size of 300nm~2um. Paclitaxel loading efficiency could reach up to 12%, and bubbles with different size and different lecithin content showed varied drug release characteristics but all displayed slow-release and ultrasound controlled properties, illustrating the ultrasound responsive drug release effect of the combination of microbubbles and ultrasound. ? (2013) Trans Tech Publications, Switzerland.
语种	英语
出处	http://dx.doi.org/10.4028/www.scientific.net/AMR.771.13
出版者	Trans Tech Publications Ltd
内容类型	其他
源URL	[http://dspace.xmu.edu.cn/handle/2288/85118]
专题	材料学院－会议论文
推荐引用方式 GB/T 7714	Wu, Shi Chao,Yang, Xiang Rui,Hou, Zhen Qing,et al. Study on biochemical materials with development of hollow and paclitaxel-loaded bubbles for ultrasound controlled drug release. 2013-01-01.

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