| 骆驼奶对1型糖尿病小鼠的辅助治疗效果; Prevention and Treatment Effect of Camel Milk on Type 1 Diabetes Mellitus | |
| 王瑞 ; 周克夫 ; 汪建红 | |
| 2015-05-28 | |
| 关键词 | 骆驼奶 小鼠 1型糖尿病 防治效果 camel milk mice type 1diabetes mellitus control effect |
| 英文摘要 | 采用预防性灌胃骆驼奶后再造模和先造模再治疗性灌胃骆驼奶两种方法,研究骆驼奶对1型糖尿病预防和辅助治疗效果.通过对各处理组(驼奶组、牛奶组、盐酸二甲双胍组及驼奶与盐酸二甲双胍联合组)小鼠空腹血糖(gluCOSE)含量、血清超氧化岐化酶(SuPErOXIdE dISMuTSE,SOd)活性、谷胱甘肽过氧化物酶(gluTATHIOnE PErOXIdASE,gSH-PX)活性、丙二醛(MAlOn dIAldEHydE,MdA)含量及甘油三酯(TrIglyCErIdE,Tg)含量的测定,并分别与对照组、糖尿病模型组比较,旨在探明骆驼奶对链脲佐菌素(STrEPTOzOTOCIn,STz)诱发的1型糖尿病模型小鼠的预防和辅助治疗作用.结果表明:骆驼奶能显著降低糖尿病小鼠空腹血糖,增加其血清SOd、gSH-PX的活性,降低血清MdA的含量.因此,骆驼奶有较好的预防和辅助治疗糖尿病的效果.; Two ways were used to prove and explain the prevention and treatment effect of camel milk on diabetes mellitus.One way was to preventively administer the normal mice by gavage with the camel milk 35 d,and then intraperitoneally inject the prevented mice with streptozotocin;the other way was to intraperitoneally inject the normal mice with streptozotocin to establish diabetes mellitus models,and then gavage with the camel milk.Finally the superoxide dismutse(SOD)and glutathione peroxidase(GSH-px)activity,blood glucose level,and malon dialdehyde(MDA),triglyceride(TG)were determined for the control group,diabetes mellitus model group,and all treatment groups.The results showed that the camel milk can significantly reduce glucose level,MDA content in blood,and also enhance SOD and GSH-px activity of diabetes mellitus mice.Therefore,the camel milk has prevention and therapeutic effects on hyperglycemia and hyperlipidemia,and can effectively enhance the anti-oxidation ability in diabetes mellitus mice.; 新疆维吾尔自治区教育厅重点实验室项目(XJSD2013-01); 新疆维吾尔自治区科技支疆项目(201191163) |
| 语种 | zh_CN |
| 内容类型 | 期刊论文 |
| 源URL | [http://dspace.xmu.edu.cn/handle/2288/108441]  |
| 专题 | 环境生态－已发表论文 |
| 推荐引用方式 GB/T 7714 | 王瑞,周克夫,汪建红. 骆驼奶对1型糖尿病小鼠的辅助治疗效果, Prevention and Treatment Effect of Camel Milk on Type 1 Diabetes Mellitus[J],2015. |
| APA | 王瑞,周克夫,&汪建红.(2015).骆驼奶对1型糖尿病小鼠的辅助治疗效果.. |
| MLA | 王瑞,et al."骆驼奶对1型糖尿病小鼠的辅助治疗效果".(2015). |
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