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	电针秩边穴与水道穴对大鼠急性脊髓损伤后运动和排尿功能的影响; Effect of electroacupuncture Zhibian( BL54) and Shuidao( ST28) on motor function and urination function in rats with acute spinal cord injuries
	Li ZM(李长明) ; Xie SJ(谢尚举) ; Quan RF(全仁夫) ; Yang ZB(杨宗保)
	2014-12-20
关键词	脊髓损伤 电针 穴 秩边 穴 水道 运动功能 膀胱容量 剩余尿量 大鼠 动物实验 Spinal cord injuries Electroacupuncture POINT BL54(ZHIBIAN) POINT ST28(SHUIDAO) Motor function Bladder capacity Residual urine volume Rats Animal experimentation
英文摘要	目的:观察电针秩边穴与水道穴对大鼠急性脊髓损伤后运动和排尿功能的影响。方法:将48只Sd大鼠随机分为电针组和对照组,每组24只。采用改良AllEn’S重物打击法将所有大鼠制成急性脊髓损伤模型。造模后24 H,电针组大鼠在秩边穴和水道穴进行电针治疗,对照组大鼠在秩边穴和水道穴旁开0.5 CM处进行电针治疗。每天治疗1次,每次15 MIn。分别于实验干预1 d、3 d、7 d和14 d后采用bbb评分法评定2组大鼠的运动功能,同时于每次运动功能测试完成后,测定大鼠的膀胱容量和剩余尿量。结果:1运动功能。干预后不同时间bbb评分的差异有统计学意义,即存在时间效应[(0.50±0.53)分,(2.90±1.10)分,(7.50±1.27)分,(11.50±0.71)分;(0.60±0.52)分,(2.70±0.95)分,(4.60±0.70)分,(8.60±0.97)分;f=625.000,P=0.000]。2组大鼠bbb评分的组间差异总体上有统计学意义,即存在分组效应(f=29.866,P=0.000);干预1 d、3 d后,2组大鼠的bbb评分比较,差异均无统计学意义(T=0.429,P=0.678;T=0.435,P=0.674);干预7 d、14 d后,电针组大鼠的bbb评分均大于对照组(T=6.328,P=0.000;T=9.222,P=0.000)。时间因素和分组因素之间存在交互效应(f=24.939,P=0.000)。2排尿功能。干预后不同时间膀胱容量的差异有统计学意义,即存在时间效应[(1.10±0.05)M l,(1.37±0.05)M l,(1.89±0.09)M l,(2.31±0.19)M l;(1.10±0.06)M l,(1.36±0.05)M l,(1.67±0.08)M l,(1.88±0.08)M l;f=193.885,P=0.000]。2组大鼠膀胱容量的组间差异总体上有统计学意义,即存在分组效应(f=65.970,P=0.000);干预1 d、3 d后,2组大鼠的膀胱容量比较,差异均无统计学意义(T=0.177,P=0.868;T=0.366,P=0.733);干预7 d、14 d后,电针组大鼠的膀胱容量均大于对照组(T=4.186,P=0.014;T=4.647,P=0.009)。时间因素和分组因素之间存在交互效应(f=10.283,P=0.000)。干预后不同时间剩余尿量的差异有统计学意义,即存在时间效应[(2.00±0.20)M l,(1.88±0.15)M l,(1.49±0.07)M l,(0.98±0.11)M l;(1.99±0.19)M l,(1.89±0.17)M l,(1.73±0.12)M l,(1.29±0.07)M l;f=131.825,P=0.000]。2组大鼠剩余尿量的组间差异总体上有统计学意义,即存在分组效应(f=3.787,P=0.038);干预1 d、3 d后,2组大鼠的剩余尿量比较,差异均无统计学意义(T=0.016,P=0.988;T=0.039,P=0.971);干预7 d、14 d后,电针组大鼠的剩余尿量均小于对照组(T=3.791,P=0.019;T=5.334,P=0.006)。时间因素和分组因素之间存在交互效应(f=5.646,P=0.028)。结论:电针秩边穴与水道穴能改善大鼠急性脊髓损伤后的运动和排尿功能。; Objective: To observe the effect of electroacupuncture Zhibian( BL54) and Shuidao( ST28) on motor function and urination function in rats with acute spinal cord injuries.Methods: Forty-eight SD rats were randomly divided into electroacupuncture group and control group,24 cases in each group.The acute spinal cord injuries models were built by modified Allen's method in all rats.The rats in the electroacupuncture group were treated with electroacupuncture at Zhibian( BL54) and Shuidao( ST28),while the others in the control group were treated with electroacupuncture at points 0.5 cm apart from Zhibian( BL54) and Shuidao( ST28) at 24 hours after the modeling,once a day for 15 minutes at a time.The motor function were evaluated by using BBB score at 1st,3rd,7th and 14 th days after experimental intervention.Meanwhile,the bladder capacity and residual urine volume of the rats were measured.Results: There was statistical difference in BBB scores between different time points after intervention,in other words,there was time effect( 0.50 + /- 0.53,2.90 + /- 1.10,7.50 + /-1.27,11.50 + /- 0.71 points; 0.60 + /- 0.52,2.70 + /- 0.95,4.60 + /- 0.70,8.60 + /- 0.97 points; F = 625.000,P = 0.000).In general,there was statistical difference in BBB scores between the 2 groups,in other words,there was grouping effect( F = 29.866,P = 0.000).There was no statistical difference in BBB scores between the 2 groups at 1 day and 3 days after intervention( t = 0.429,P = 0.678; t =0.435,P = 0.674),and the BBB scores of the electroacupuncture group were greater than those of control group at 7 and 14 days after intervention( t = 6.328,P = 0.000; t = 9.222,P = 0.000).There was interaction between time factor and grouping factor( F = 24.939,P =0.000).There was statistical difference in bladder capacity between different time points after intervention,in other words,there was time effect( 1.10 + /- 0.05,1.37 + /- 0.05,1.89 + /- 0.09,2.31 + /- 0.19 m L; 1.10 + /- 0.06,1.36 + /- 0.05,1.67 + /- 0.08,1.88 + /-0.08 m L; F = 193.885,P = 0.000).In general,there was statistical difference in bladder capacity between the 2 groups,in other words,there was grouping effect( F = 65.970,P = 0.000).There was no statistical difference in bladder capacity between the 2 groups at 1 day and 3 days after intervention( t = 0.177,P = 0.868; t = 0.366,P = 0.733),and the bladder capacity of the electroacupuncture group was larger than that of control group at 7 and 14 days after intervention( t = 4.186,P = 0.014; t = 4.647,P = 0.009).There was interaction between time factor and grouping factor( F = 10.283,P = 0.000).There was statistical difference in residual urine volume between different time points after intervention,in other words,there was time effect( 2.00 + /- 0.20,1.88 + /- 0.15,1.49 + /- 0.07,0.98 + /- 0.11 m L;1.99 + /- 0.19,1.89 + /- 0.17,1.73 + /- 0.12,1.29 + /- 0.07 m L; F = 131.825,P = 0.000).In general,there was statistical difference in residual urine volume between the 2 groups,in other words,there was grouping effect( F = 3.787,P = 0.038).There was no statistical difference in residual urine volume between the 2 groups at 1 day and 3 days after intervention( t = 0.016,P = 0.988; t = 0.039,P =0.971),and the residual urine volume of the electroacupuncture group was smaller than that of control group at 7 and 14 days after intervention( t = 3.791,P = 0.019; t = 5.334,P = 0.006).There was interaction between time factor and grouping factor( F = 5.646,P =0.028).Conclusion: The motor function and urination function of rats with acute spinal cord injuries can be improved by electroacupuncture Zhibian( BL54) and Shuidao( ST28).; 浙江省中医药科研计划项目(2008CB067)
语种	zh_CN
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/123714]
专题	医学院－已发表论文
推荐引用方式 GB/T 7714	李长明,谢尚举,全仁夫,等. 电针秩边穴与水道穴对大鼠急性脊髓损伤后运动和排尿功能的影响, Effect of electroacupuncture Zhibian( BL54) and Shuidao( ST28) on motor function and urination function in rats with acute spinal cord injuries[J],2014.
APA	李长明,谢尚举,全仁夫,&杨宗保.(2014).电针秩边穴与水道穴对大鼠急性脊髓损伤后运动和排尿功能的影响..
MLA	李长明,et al."电针秩边穴与水道穴对大鼠急性脊髓损伤后运动和排尿功能的影响".(2014).

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