Laparoscopic versus open distal pancreatectomy: A meta-analysis

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	Laparoscopic versus open distal pancreatectomy: A meta-analysis
	Sui, Cheng-Jun ; Li, Bin ; Yang, Jia-Mei ; Wang, Shuang-Jia ; Zhou, Yan-Ming ; Li B(李滨) ; Zhou YM(周彦明)
刊名	http://dx.doi.org/10.1016/j.asjsur.2012.04.001
	2012-01
关键词	SINGLE-INSTITUTION CLINICAL-OUTCOMES RESECTION PANCREAS SURGERY BENIGN INSULINOMAS EXPERIENCE DISEASE SPLEEN
英文摘要	Objective: Laparoscopic distal pancreatectomy (LDP) is a minimally invasive surgical technique. The aim of the present study was to evaluate the currently available literature and compare the short-term clinical outcomes of patients who underwent LDP for left-sided pancreatic pathology with patients who underwent traditional open surgery. Methods: A literature search was performed to identify and compare studies that reported the clinical outcomes of both LDP and open distal pancreatectomy (ODP). Pooled odds ratios (OR) and weighted mean differences (WMD) with 95% confidence intervals (95% Cl) were calculated using either fixed-effects or random-effects models. Results: Nineteen nonrandomized controlled studies were identified that matched the selection criteria and reported the clinical outcomes of 1935 patients, of whom 805 underwent LDP and 1130 underwent ODP. Compared with open surgery, reports on laparoscopic resection indicate potentially favorable outcomes in terms of operative blood loss (WMD: -273.11; 95% CI: -404.61 to -141.61), the requirement of a blood transfusion (OR: 0.28; 95% CI: 0.11 -0.71), postoperative time until oral intake (WMD: -1.19; 95% CI: -1.87 to -0.50), time to first flatus (WMD: -1.03, 95% CI: -1.93 to -0.12), length of hospital stay (WMD: -3.87, 95% CI: -5.06 to -2.68), and overall morbidity (OR: 0.70, 95% CI: 0.56-0.87). There were no differences in terms of the extent of oncologic clearance and postoperative mortality. Conclusion: LDP results in a faster postoperative recovery and a comparable oncologic clearance in comparison with open surgery. Additional large trials are required to delineate the long-term clinical outcomes of patients diagnosed with malignant neoplasms who undergo either of these two surgeries. Copyright (C) 2012, Asian Surgical Association. Published by Elsevier Taiwan LLC. All rights reserved.
语种	英语
出版者	ASIAN J SURG
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/93338]
专题	医学院－已发表论文
推荐引用方式 GB/T 7714	Sui, Cheng-Jun,Li, Bin,Yang, Jia-Mei,et al. Laparoscopic versus open distal pancreatectomy: A meta-analysis[J]. http://dx.doi.org/10.1016/j.asjsur.2012.04.001,2012.
APA	Sui, Cheng-Jun.,Li, Bin.,Yang, Jia-Mei.,Wang, Shuang-Jia.,Zhou, Yan-Ming.,...&周彦明.(2012).Laparoscopic versus open distal pancreatectomy: A meta-analysis.http://dx.doi.org/10.1016/j.asjsur.2012.04.001.
MLA	Sui, Cheng-Jun,et al."Laparoscopic versus open distal pancreatectomy: A meta-analysis".http://dx.doi.org/10.1016/j.asjsur.2012.04.001 (2012).