Bayesian inferences for beta semiparametric-mixed models to analyze longitudinal neuroimaging data

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	Bayesian inferences for beta semiparametric-mixed models to analyze longitudinal neuroimaging data
	Wang, Xiao-Feng ; Li, Yingxing ; Li YX(李迎星)
刊名	http://dx.doi.org/10.1002/bimj.201300003
	2014
关键词	PENALIZED SPLINES REGRESSION ERRORS
英文摘要	NIH [UL1 RR024989]; NSF of China [11201390]; NSF of Fujian [2013J01024]; Diffusion tensor imaging (DTI) is a quantitative magnetic resonance imaging technique that measures the three-dimensional diffusion of water molecules within tissue through the application of multiple diffusion gradients. This technique is rapidly increasing in popularity for studying white matter properties and structural connectivity in the living human brain. One of the major outcomes derived from the DTI process is known as fractional anisotropy, a continuous measure restricted on the interval (0,1). Motivated from a longitudinal DTI study of multiple sclerosis, we use a beta semiparametric-mixed regression model for the neuroimaging data. This work extends the generalized additive model-methodology with beta distribution family and random effects. We describe two estimation methods with penalized splines, which are formalized under a Bayesian inferential perspective. The first one is carried out by Markov chain Monte Carlo (MCMC) simulations while the second one uses a relatively new technique called integrated nested Laplace approximation (INLA). Simulations and the neuroimaging data analysis show that the estimates obtained from both approaches are stable and similar, while the INLA method provides an efficient alternative to the computationally expensive MCMC method.
语种	英语
出版者	WILEY-BLACKWELL
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/91537]
专题	王亚南院－已发表论文
推荐引用方式 GB/T 7714	Wang, Xiao-Feng,Li, Yingxing,Li YX. Bayesian inferences for beta semiparametric-mixed models to analyze longitudinal neuroimaging data[J]. http://dx.doi.org/10.1002/bimj.201300003,2014.
APA	Wang, Xiao-Feng,Li, Yingxing,&李迎星.(2014).Bayesian inferences for beta semiparametric-mixed models to analyze longitudinal neuroimaging data.http://dx.doi.org/10.1002/bimj.201300003.
MLA	Wang, Xiao-Feng,et al."Bayesian inferences for beta semiparametric-mixed models to analyze longitudinal neuroimaging data".http://dx.doi.org/10.1002/bimj.201300003 (2014).