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	Antibiotic resistance pattern of Klebsiella pneumoniae and Enterobacter sakazakii isolates from powdered infant formula
	Zhou, Xianfeng ; Gao, Jianxin ; Huang, Yaojian ; Fu, Songzhe ; Chen, Haiying ; Huang YJ(黄耀坚)
	2011-09-23
关键词	SPECTRUM BETA-LACTAMASES INTENSIVE-CARE-UNIT MILK FORMULA NEONATAL MENINGITIS ESCHERICHIA-COLI EPIDEMIOLOGY INFECTIONS PATHOGEN OUTBREAK CHILDREN
英文摘要	Morbidity and mortality of infant infections caused by contaminated powdered infant formula (PIF) have been reported worldwide, and pathogens like Enterobacter sakazakii and Klebsiella pneumoniae are important causative agents. To evaluate the prevalence of antibiotic resistance in E. sakazakii and K. pneumoniae that caused PIF contamination in Chinese market, all the isolates from PIF were analyzed for detecting resistance to antibiotics. 30 PIF samples were randomly purchased in Chinese market in 2009 and 7 E. sakazakii and 6 K. pneumoniae isolates were obtained from 8 samples (26.7%), the isolates were evaluated for antibiotics susceptibility by disk diffusion technique as recommended by the Clinical Laboratory Standards Institute (CLSI). Susceptibility results showed that each isolate had different levels of resistance to beta-lactam antibiotics, while sensitive to fluoroquinolones and aminoglycosides. One K. pneumoniae and one E. sakazakii isolate almost resisted all Cephalosporins chosen; the double-disk synergy test (DDST) showed these two isolates producing extended spectrum beta-lactamase (ESBL). This is the first report of ESBL-produing in E. sakazakii from powdered infant formula in China.
语种	英语
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/65970]
专题	生命科学－已发表论文
推荐引用方式 GB/T 7714	Zhou, Xianfeng,Gao, Jianxin,Huang, Yaojian,et al. Antibiotic resistance pattern of Klebsiella pneumoniae and Enterobacter sakazakii isolates from powdered infant formula[J],2011.
APA	Zhou, Xianfeng,Gao, Jianxin,Huang, Yaojian,Fu, Songzhe,Chen, Haiying,&黄耀坚.(2011).Antibiotic resistance pattern of Klebsiella pneumoniae and Enterobacter sakazakii isolates from powdered infant formula..
MLA	Zhou, Xianfeng,et al."Antibiotic resistance pattern of Klebsiella pneumoniae and Enterobacter sakazakii isolates from powdered infant formula".(2011).

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