Serological survey of antibodies to influenza A viruses in a group of people without a history of influenza vaccination | |
Xia, N. ; Chen, Y. ; Chen YX(陈毅歆) ; Zheng, Q. ; Yang, K. ; Zeng, F. ; Lau, S. -Y. ; Wu, W. L. ; Huang, S. ; Zhang, J. ; Chen, H | |
2011-06-28 | |
关键词 | Antibody H9N2 influenza pandemic H1N1 prevalence |
英文摘要 | A serological survey for antibodies to influenza viruses was performed in China on a group of people without a history of influenza vaccination. Using the haemagglutination inhibition (HI) assay, we found seropositivity rates for seasonal H3N2 to be significantly higher than those for seasonal H1N1. Samples positive for antibodies to the pandemic (H1N1) 2009 virus increased from 0.6% pre-outbreak to 4.5% (p <0.01) at 1 year post-outbreak. Interestingly, HI and neutralization tests showed that 1.4% of people in the group have antibodies recognizing H9N2 avian influenza viruses, suggesting that infection with this subtype may be more common than previously thought.; National Natural Science Foundation of China[30901077]; Key Project of the National 863 Program of China[2010AA022801]; Natural Science Foundation of Fujian Province in China[2010J05083]; University Grants Committee[AoE/M-12/06]; National Institutes of Health (NIAID)[HHSN2662007 00005C]; Research Fund for the Control of Infectious Diseases, Hong Kong SAR, China |
语种 | 英语 |
出版者 | WILEY-BLACKWELL |
内容类型 | 期刊论文 |
源URL | [http://dx.doi.org/doi:10.1111/j.1469-0691.2011.03538.x] ![]() |
专题 | 生命科学-已发表论文 |
推荐引用方式 GB/T 7714 | Xia, N.,Chen, Y.,Chen YX,et al. Serological survey of antibodies to influenza A viruses in a group of people without a history of influenza vaccination[J],2011. |
APA | Xia, N..,Chen, Y..,陈毅歆.,Zheng, Q..,Yang, K..,...&Chen, H.(2011).Serological survey of antibodies to influenza A viruses in a group of people without a history of influenza vaccination.. |
MLA | Xia, N.,et al."Serological survey of antibodies to influenza A viruses in a group of people without a history of influenza vaccination".(2011). |
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