Au@pt nanoparticle encapsulated target-responsive hydrogel with volumetric bar-chart chip readout for quantitative point-of-care testing

CORC > 厦门大学 > 化学化工－已发表论文

	Au@pt nanoparticle encapsulated target-responsive hydrogel with volumetric bar-chart chip readout for quantitative point-of-care testing
	Zhu, Zhi ; Guan, Zhichao ; Jia, Shasha ; Lei, Zhichao ; Lin, Shuichao ; Zhang, Huimin ; Ma, Yanli ; Tian, Zhong-Qun ; Yang, Chaoyong James ; Zhu Z(朱志) ; Lin SC(林水潮) ; Tian ZQ(田中群) ; Yang CY(杨朝勇)
刊名	http://dx.doi.org/10.1002/anie.201405995
	2014
关键词	Gold Microfluidics Nanoparticles
英文摘要	Point-of-care testing (POCT) with the advantages of speed, simplicity, portability, and low cost is critical for the measurement of analytes in a variety of environments where access to laboratory infrastructure is lacking. While qualitative POCTs are widely available, quantitative POCTs present significant challenges. Here we describe a novel method that integrates an Au core/Pt shell nanoparticle (Au@PtNP) encapsulated target-responsive hydrogel with a volumetric bar-chart chip (V-Chip) for quantitative POCT. Upon target introduction, the hydrogel immediately dissolves and releases Au@PtNPs, which can efficiently catalyze the decomposition of H2O2 to generate a large volume of O2 to move of an ink bar in the V-Chip. The concentration of the target introduced can be visually quantified by reading the traveling distance of the ink bar. This method has the potential to be used for portable and quantitative detection of a wide range of targets without any external instrument.
语种	英语
出版者	Wiley-VCH Verlag
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/89782]
专题	化学化工－已发表论文
推荐引用方式 GB/T 7714	Zhu, Zhi,Guan, Zhichao,Jia, Shasha,et al. Au@pt nanoparticle encapsulated target-responsive hydrogel with volumetric bar-chart chip readout for quantitative point-of-care testing[J]. http://dx.doi.org/10.1002/anie.201405995,2014.
APA	Zhu, Zhi.,Guan, Zhichao.,Jia, Shasha.,Lei, Zhichao.,Lin, Shuichao.,...&杨朝勇.(2014).Au@pt nanoparticle encapsulated target-responsive hydrogel with volumetric bar-chart chip readout for quantitative point-of-care testing.http://dx.doi.org/10.1002/anie.201405995.
MLA	Zhu, Zhi,et al."Au@pt nanoparticle encapsulated target-responsive hydrogel with volumetric bar-chart chip readout for quantitative point-of-care testing".http://dx.doi.org/10.1002/anie.201405995 (2014).