Anodic TiO2 Nanotubular Arrays with Pre-Synthesized Hydroxyapatite-An Effective Approach to Enhance the Biocompatibility of Titanium | |
Wang, Lu-Ning ; Lin, Long-Xiang ; Lin, Chang-Jian ; Shen, Chen ; Shinbine, Alyssa ; Luo, Jing-Li ; Lin CJ(林昌健) | |
刊名 | http://dx.doi.org/10.1166/jnn.2013.7458 |
2013 | |
关键词 | SIMULATED BODY-FLUID CALCIUM-PHOSPHATE COATINGS MECHANICAL-PROPERTIES CORROSION BEHAVIOR IMPLANT MATERIALS SURFACE APATITE GROWTH DEPOSITION ALLOYS |
英文摘要 | Natural Sciences and Engineering Research Council Canada; National Natural Science Foundation of China [21021002]; National Scientific Support Program of China [2012BAI07B09]; Electrochemically anodized TiO2 nanotubular arrays can provide large surface areas for biological species attachment. In order to further enhance the biocompatibility of Ti medical implants, we deposited a pre-synthesized hydroxyapatite inside and on the nanotubular arrays, and examined the biocompatibility of the anodized TiO2 nanotubular arrays with pre-synthesized hydroxyapatite by in vitro assessment in simulated body fluid, and in vitro cell culture. The results showed that the hydroxyapatite coating was able to be induced on TiO2 nanotubular arrays with pre-synthesized hydroxyapatite within 5 days while only a thin film composed of calcium phosphorous chemicals formed on as-formed TiO2 nanotubular arrays. The cell culture evaluation further proved the enhancement of cell attachment and proliferation on TiO2 nanotubular arrays with pre-synthesized hydroxyapatite as opposed to those without pre-synthesized hydroxyapatite. The present study proves that formation of TiO2 nanotubular arrays with pre-synthesized hydroxyapatite a promising method to enhance the biocompatibility of Ti implants. |
语种 | 英语 |
出版者 | AMER SCIENTIFIC PUBLISHERS |
内容类型 | 期刊论文 |
源URL | [http://dspace.xmu.edu.cn/handle/2288/88961] |
专题 | 化学化工-已发表论文 |
推荐引用方式 GB/T 7714 | Wang, Lu-Ning,Lin, Long-Xiang,Lin, Chang-Jian,et al. Anodic TiO2 Nanotubular Arrays with Pre-Synthesized Hydroxyapatite-An Effective Approach to Enhance the Biocompatibility of Titanium[J]. http://dx.doi.org/10.1166/jnn.2013.7458,2013. |
APA | Wang, Lu-Ning.,Lin, Long-Xiang.,Lin, Chang-Jian.,Shen, Chen.,Shinbine, Alyssa.,...&林昌健.(2013).Anodic TiO2 Nanotubular Arrays with Pre-Synthesized Hydroxyapatite-An Effective Approach to Enhance the Biocompatibility of Titanium.http://dx.doi.org/10.1166/jnn.2013.7458. |
MLA | Wang, Lu-Ning,et al."Anodic TiO2 Nanotubular Arrays with Pre-Synthesized Hydroxyapatite-An Effective Approach to Enhance the Biocompatibility of Titanium".http://dx.doi.org/10.1166/jnn.2013.7458 (2013). |
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