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Anodic TiO2 Nanotubular Arrays with Pre-Synthesized Hydroxyapatite-An Effective Approach to Enhance the Biocompatibility of Titanium
Wang, Lu-Ning ; Lin, Long-Xiang ; Lin, Chang-Jian ; Shen, Chen ; Shinbine, Alyssa ; Luo, Jing-Li ; Lin CJ(林昌健)
刊名http://dx.doi.org/10.1166/jnn.2013.7458
2013
关键词SIMULATED BODY-FLUID CALCIUM-PHOSPHATE COATINGS MECHANICAL-PROPERTIES CORROSION BEHAVIOR IMPLANT MATERIALS SURFACE APATITE GROWTH DEPOSITION ALLOYS
英文摘要Natural Sciences and Engineering Research Council Canada; National Natural Science Foundation of China [21021002]; National Scientific Support Program of China [2012BAI07B09]; Electrochemically anodized TiO2 nanotubular arrays can provide large surface areas for biological species attachment. In order to further enhance the biocompatibility of Ti medical implants, we deposited a pre-synthesized hydroxyapatite inside and on the nanotubular arrays, and examined the biocompatibility of the anodized TiO2 nanotubular arrays with pre-synthesized hydroxyapatite by in vitro assessment in simulated body fluid, and in vitro cell culture. The results showed that the hydroxyapatite coating was able to be induced on TiO2 nanotubular arrays with pre-synthesized hydroxyapatite within 5 days while only a thin film composed of calcium phosphorous chemicals formed on as-formed TiO2 nanotubular arrays. The cell culture evaluation further proved the enhancement of cell attachment and proliferation on TiO2 nanotubular arrays with pre-synthesized hydroxyapatite as opposed to those without pre-synthesized hydroxyapatite. The present study proves that formation of TiO2 nanotubular arrays with pre-synthesized hydroxyapatite a promising method to enhance the biocompatibility of Ti implants.
语种英语
出版者AMER SCIENTIFIC PUBLISHERS
内容类型期刊论文
源URL[http://dspace.xmu.edu.cn/handle/2288/88961]  
专题化学化工-已发表论文
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GB/T 7714
Wang, Lu-Ning,Lin, Long-Xiang,Lin, Chang-Jian,et al. Anodic TiO2 Nanotubular Arrays with Pre-Synthesized Hydroxyapatite-An Effective Approach to Enhance the Biocompatibility of Titanium[J]. http://dx.doi.org/10.1166/jnn.2013.7458,2013.
APA Wang, Lu-Ning.,Lin, Long-Xiang.,Lin, Chang-Jian.,Shen, Chen.,Shinbine, Alyssa.,...&林昌健.(2013).Anodic TiO2 Nanotubular Arrays with Pre-Synthesized Hydroxyapatite-An Effective Approach to Enhance the Biocompatibility of Titanium.http://dx.doi.org/10.1166/jnn.2013.7458.
MLA Wang, Lu-Ning,et al."Anodic TiO2 Nanotubular Arrays with Pre-Synthesized Hydroxyapatite-An Effective Approach to Enhance the Biocompatibility of Titanium".http://dx.doi.org/10.1166/jnn.2013.7458 (2013).
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