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	Accelerating biocatalytic process design: Integrating new tools from biology, chemistry and engineering
	Baganz, F ; Chen, B ; Dalby, P ; Hibbert, E ; Lye, G ; Micheletti, M ; Woodley, J ; Kaulmann, U ; Ward, J ; Hailes, H ; Smith, M ; Smithies, K ; Chen BH(陈秉辉)
	2007
英文摘要	Biocatalysis is a powerful technique for the efficient synthesis of optically pure pharmaceuticals that are difficult to access via conventional chemistry. Although now widely implemented, the ability to design first generation processes in the timeframes achievable using chemical syntheses remains a challenge. This presentation will describe the outcomes of a multidisciplinary programme that has speed to process as its focus. The enzymes transketolase (TK) and transaminase (TAm), respectively, catalyse asymmetric carbon–carbon bond formation and amine group addition. The synthesis of a range of chiral amino alcohols from simple achiral substrates using these two enzymes has been used to exemplify the approach.
语种	英语
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/64198]
专题	化学化工－已发表论文
推荐引用方式 GB/T 7714	Baganz, F,Chen, B,Dalby, P,et al. Accelerating biocatalytic process design: Integrating new tools from biology, chemistry and engineering[J],2007.
APA	Baganz, F.,Chen, B.,Dalby, P.,Hibbert, E.,Lye, G.,...&陈秉辉.(2007).Accelerating biocatalytic process design: Integrating new tools from biology, chemistry and engineering..
MLA	Baganz, F,et al."Accelerating biocatalytic process design: Integrating new tools from biology, chemistry and engineering".(2007).

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