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General and efficient copper-catalyzed amidation of saturated C-H bonds using N-halosuccinimides as the oxidants
Liu, X. W. ; Zhang, Y. M. ; Wang, L. ; Fu, H. ; Jiang, Y. Y. ; Zhao, Y. F. ; Zhao YF(赵玉芬)
2008
关键词CARBON-HYDROGEN BONDS CHLORAMINE-T NITROGEN ATOM BROMAMINE-T INTRAMOLECULAR AMIDATION NITRENE SOURCE AMINATION AZIRIDINATION FUNCTIONALIZATION ACTIVATION
英文摘要We have developed a general and efficient method for copper-catalyzed amidation of saturated C-H bonds under mild conditions, and the used substrates include benzylic reagents, the N,N-dimethylaniline derivatives, the free carboxamides, and sulfonamides. The protocol uses inexpensive and readily available CuBr/N-halosuccinimide (NBS or NCS) as the catalyst/oxidant, so it provides practical applications for synthesis of various amides via C-H activation.
语种英语
内容类型期刊论文
源URL[http://dspace.xmu.edu.cn/handle/2288/63660]  
专题化学化工-已发表论文
推荐引用方式
GB/T 7714
Liu, X. W.,Zhang, Y. M.,Wang, L.,et al. General and efficient copper-catalyzed amidation of saturated C-H bonds using N-halosuccinimides as the oxidants[J],2008.
APA Liu, X. W..,Zhang, Y. M..,Wang, L..,Fu, H..,Jiang, Y. Y..,...&赵玉芬.(2008).General and efficient copper-catalyzed amidation of saturated C-H bonds using N-halosuccinimides as the oxidants..
MLA Liu, X. W.,et al."General and efficient copper-catalyzed amidation of saturated C-H bonds using N-halosuccinimides as the oxidants".(2008).
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