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RETRACTED ARTICLE: Quantification of PAHs pollution in marine environment by measurements of EROD activity and Caspase-3/7 activity in marine madaka (Oryzias melastigma) embryos
Lin, Xiao-Long ; Wang, Xin-Hong ; Zhao, Yan-Yan ; Hong, Hua-Sheng ; Mu, Jing-Li ; Fang, Chao ; Wang XH(王新红) ; Hong HS(洪华生)
刊名http://dx.doi.org/10.1109/icbbe.2011.5781420
2011
关键词Anthracene Aromatic hydrocarbons Bioinformatics Biomarkers Biomedical engineering Pollution
英文摘要Marine model fish medaka and their embryos can be used as an ideal research materials in the field of marine ecotoxicology due to their highly sensitive to various environmental pollutants. In this study, we took marine medaka (Oryzias melastigma) and their embryos as subject materials, and used the activities of embryonic EROD (7-ethoxyresorufin-O-deethylase) and Caspase-3/7 as biomarkers to study the typical polycyclic aromatic hydrocarbon (PAH) such as benzo (a) pyrene, phenanthrene and pyrene induced the toxicity and dose-response relationship of marine fish. The results showed that both of EROD activity and Caspase-3/7 activity in embryos could be induced by benzo(a)pyrene, phenanthrene and pyrene significantly. In particular, the significant induction of EROD activity by specific PAHs can be used for early warning and PAHs detection in the marine environment. The Caspase-3/7 in the fertilized eggs(1-3 dpf) can also be significantly induced by PAHs which can be used to monitor PAHs pollution as another promising biomarkers. In general, these methods to quantify and assess PAHs pollution in the marine environment are sensitive and have good application prospects. ? 2011 IEEE.
语种英语
出版者IEEE Computer Society
内容类型期刊论文
源URL[http://dspace.xmu.edu.cn/handle/2288/88290]  
专题海洋环境-已发表论文
推荐引用方式
GB/T 7714
Lin, Xiao-Long,Wang, Xin-Hong,Zhao, Yan-Yan,et al. RETRACTED ARTICLE: Quantification of PAHs pollution in marine environment by measurements of EROD activity and Caspase-3/7 activity in marine madaka (Oryzias melastigma) embryos[J]. http://dx.doi.org/10.1109/icbbe.2011.5781420,2011.
APA Lin, Xiao-Long.,Wang, Xin-Hong.,Zhao, Yan-Yan.,Hong, Hua-Sheng.,Mu, Jing-Li.,...&洪华生.(2011).RETRACTED ARTICLE: Quantification of PAHs pollution in marine environment by measurements of EROD activity and Caspase-3/7 activity in marine madaka (Oryzias melastigma) embryos.http://dx.doi.org/10.1109/icbbe.2011.5781420.
MLA Lin, Xiao-Long,et al."RETRACTED ARTICLE: Quantification of PAHs pollution in marine environment by measurements of EROD activity and Caspase-3/7 activity in marine madaka (Oryzias melastigma) embryos".http://dx.doi.org/10.1109/icbbe.2011.5781420 (2011).
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