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	Hyaluronic Acid/Polylysine Hydrogel as a Transfer System for Transplantation of Neural Stem Cells
	Ren, Yong-Juan ; Zhou, Zi-You ; Cui, Fu-Zhai
	2010-10-12 ; 2010-10-12
关键词	neural stem cell tissue engineering tissue scaffolds stem cell transplantation hydrogels hyaluronic acid hydrogels polylysine hydrogels hyaluronic acid/polylysine hydrogels TRAUMATIC BRAIN-INJURY REPAIR REGENERATION TISSUE Biotechnology & Applied Microbiology Materials Science, Biomaterials Polymer Science
中文摘要	Graft integration and survival are major factors that limit cell therapy for diseases and injury in the central nervous system. Efforts to improve graft survival and integration have focused on the development of biocompatible scaffolds to support neural cells. In this study, rat neural stem cells (NSC), including neurospheres and single cells, were seeded into hyaluronic acid/polylysine hydrogels. Confocal microscopy was used to noninvasively investigate the key cell phonotypes. After culture for 5 days, single NSC had survived and differentiated into neurons and astrocytes, while neurosphere-forming cells had migrated from their original aggregate and maintained the NSC phonotype. These studies, carried out in the absence of serum, identified HA/polylysine hydrogels as potential synthetic cell carriers for transplantation of NSC.
语种	英语 ; 英语
出版者	SAGE PUBLICATIONS LTD ; LONDON ; 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND
内容类型	期刊论文
源URL	[http://hdl.handle.net/123456789/78449]
专题	清华大学
推荐引用方式 GB/T 7714	Ren, Yong-Juan,Zhou, Zi-You,Cui, Fu-Zhai. Hyaluronic Acid/Polylysine Hydrogel as a Transfer System for Transplantation of Neural Stem Cells[J],2010, 2010.
APA	Ren, Yong-Juan,Zhou, Zi-You,&Cui, Fu-Zhai.(2010).Hyaluronic Acid/Polylysine Hydrogel as a Transfer System for Transplantation of Neural Stem Cells..
MLA	Ren, Yong-Juan,et al."Hyaluronic Acid/Polylysine Hydrogel as a Transfer System for Transplantation of Neural Stem Cells".(2010).

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