| Calcium near the release site is essential for basal ACh release in Xenopus | |
| Li, Ruxin ; Lei, Qi ; Song, Ge ; He, Xiangping ; Xie, Zuoping | |
| 2010-05-11 ; 2010-05-11 | |
| 关键词 | Calcium Basal neurotransmitter release Spontaneous synaptic currents DEVELOPING NEUROMUSCULAR SYNAPSES SPONTANEOUS TRANSMITTER RELEASE PERMEABILITY TRANSITION PORE SYNAPTIC VESICLE CYCLE NEUROTRANSMITTER RELEASE ENDOPLASMIC-RETICULUM CA2+ RELEASE STORES NEURONS ACETYLCHOLINE Cell Biology |
| 中文摘要 | Extracellular calcium is essential for neurotransmitter release, but the detailed mechanism by which Ca2+ regulates basal synaptic release has not yet been fully explored. In this study, calcium imaging and the whole-cell patch-clamp technique were used to investigate the role of Ca2+ in basal acetylcholine (ACh) release in the Xenopus neuromuscular junction and in isolated myocytes exogenously loaded with ACh. Carried out in normal and Ca2+-free extracellular solution, the results indicate that Ca2+ near the release site is essential for basal neurotransmitter release. (C) 2008 International Federation for Cell Biology. Published by Elsevier Ltd. All rights reserved. |
| 语种 | 英语 ; 英语 |
| 出版者 | ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD ; LONDON ; 24-28 OVAL RD, LONDON NW1 7DX, ENGLAND |
| 内容类型 | 期刊论文 |
| 源URL | [http://hdl.handle.net/123456789/26867]  |
| 专题 | 清华大学 |
| 推荐引用方式 GB/T 7714 | Li, Ruxin,Lei, Qi,Song, Ge,et al. Calcium near the release site is essential for basal ACh release in Xenopus[J],2010, 2010. |
| APA | Li, Ruxin,Lei, Qi,Song, Ge,He, Xiangping,&Xie, Zuoping.(2010).Calcium near the release site is essential for basal ACh release in Xenopus.. |
| MLA | Li, Ruxin,et al."Calcium near the release site is essential for basal ACh release in Xenopus".(2010). |
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