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	Attention-induced frontal brain activation in adolescents using near-infrared imaging
	Zhang, Yonghong ; Fan, Xiaofei ; Liu, Jiacheng ; Bai, Jing ; Peng, Miao ; Shuai, Lan ; Wang, Yufeng
	2010-05-10 ; 2010-05-10
会议名称	WORLD CONGRESS ON MEDICAL PHYSICS AND BIOMEDICAL ENGINEERING 2006, VOL 14, PTS 1-6 ; World Congress on Medical Physics and Biomedical Engineering ; Seoul, SOUTH KOREA ; Web of Science
关键词	Near-infrared imaging Brain activation Stroop test SPECTROSCOPY Engineering, Biomedical Physics, Applied Imaging Science & Photographic Technology
中文摘要	Brain activities can be monitored non-invasively by near-infrared spectroscopy and imaging technique, which has several advantages in comparison with other imaging methods, such as less restraining, high temporal resolution, and biochemical specificity. The aim of our study was to examine the feasibility of our NIR imaging system in functional brain activation studies with cognition paradigms. The continuous wave NIR imaging system has been developed in our lab, which consists of 9 sources and 4 detectors. The wavelength of 808 nm laser diode is used as light source. With measurement of relative changes from some baseline, serials of images can be reconstructed corresponding to the variety of regional cerebral blood volume (rCBV) during cognitive tests or in clinical situation. The study included 12 subjects (male; mean age =14.6) with attention deficit hyperactivity disorder (ADHD) and 13 healthy comparison subjects (2 female and 11 male; mean age =14.2). These adolescents consent underwent NIR imaging for the frontal cortex while performance a version of the color-naming Stroop tests. The tests procedure included three test cycles interrupted by relax breaks. In the course of the test, a significant increase of rCBV was observed in the right frontal region for the comparison subjects, whereas a significant increase of rCBV was observed on both sides for the subjects with ADHD. Brain activation leads to an increase in cerebral blood flow and volume. The results are in accordance with the reports on a reduction in prefrontal volume, predominantly in the right hemisphere.
会议录出版者	SPRINGER-VERLAG BERLIN ; BERLIN ; HEIDELBERGER PLATZ 3, D-14197 BERLIN, GERMANY
语种	英语 ; 英语
内容类型	会议论文
源URL	[http://hdl.handle.net/123456789/20221]
专题	清华大学
推荐引用方式 GB/T 7714	Zhang, Yonghong,Fan, Xiaofei,Liu, Jiacheng,et al. Attention-induced frontal brain activation in adolescents using near-infrared imaging[C]. 见:WORLD CONGRESS ON MEDICAL PHYSICS AND BIOMEDICAL ENGINEERING 2006, VOL 14, PTS 1-6, World Congress on Medical Physics and Biomedical Engineering, Seoul, SOUTH KOREA, Web of Science.

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