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	Adenine detection by photonic crystal fiber based surface enhanced Raman scattering probe - art. no. 683802
	Li, Mingshan ; Yang, Changxi ; Yan, He ; Jin, Guofan
	2010-05-10 ; 2010-05-10
会议名称	OPTOELECTRONIC DEVICES AND INTEGRATION II ; 2nd Conference on Optoelectronic Devices and Integration ; Beijing, PEOPLES R CHINA ; Web of Science
关键词	SERS PCF biomolecule adenine SPECTROSCOPY SERS GEOMETRY SENSORS Engineering, Electrical & Electronic Optics
中文摘要	Detection of biological samples in low concentration is of great significance to the basic research in science, the development of medical technology and many other fields related to our lives. Surface-Enhanced Raman Scattering (SERS), well-known as a powerful analytical tool with high sensitivity, is especially suitable for biomolecule detection as it enables near infrared (NIR) excitation and label-free detection. SERS probe made of conventional optical fiber provides better flexibility in detection; however, it requires a complicated fabrication process and doesn't serve as a well-set detecting platform. In this talk we propose and demonstrate a photonic crystal fiber (PCF) based SERS probe, which has the new advantages of simplicity in fabrication, better light confinement and increased light-analyte interaction volume. The PCF-based SERS probes are prepared in three different ways: mixed solution of sample and gold nanoparticles filled in air holes of PCF, sample solution dried in gold coated air holes and sample solution filled in gold coated air holes, respectively. Sample solution of adenine is in concentration of about 10(-6)M. Almost every characteristic peak of adenine can be observed in the spectra detected by each of the three probes.
会议录出版者	SPIE-INT SOC OPTICAL ENGINEERING ; BELLINGHAM ; 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA
语种	英语 ; 英语
内容类型	会议论文
源URL	[http://hdl.handle.net/123456789/19477]
专题	清华大学
推荐引用方式 GB/T 7714	Li, Mingshan,Yang, Changxi,Yan, He,et al. Adenine detection by photonic crystal fiber based surface enhanced Raman scattering probe - art. no. 683802[C]. 见:OPTOELECTRONIC DEVICES AND INTEGRATION II, 2nd Conference on Optoelectronic Devices and Integration, Beijing, PEOPLES R CHINA, Web of Science.

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