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	In vitro degradation of porous nano-hydroxyapatite/collagen/PLLA scaffold reinforced by chitin fibres
	Li, XM ; Feng, QL ; Cui, FZ
	2010-05-10 ; 2010-05-10 ; OCT 04-06, 2004
会议名称	MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS ; 2nd Asia Symnposium on Biomineralization ; Beijing, PEOPLES R CHINA ; Web of Science
关键词	chitin fibres degradation in vitro scaffold bone tissue engineering COLLAGEN CHITOSAN PROLIFERATION DERIVATIVES FIBROBLASTS COMPOSITES BIOREACTOR COMPLEXES POLYMERS CULTURE Materials Science, Multidisciplinary
中文摘要	In this paper, a novel porous scaffold for bone tissue engineering was prepared with nano-hydroxyapatite/collagen/Poly-L-lactic acid (PLLA) composite reinforced by chitin fibres. To enhance the strength of the scaffold further, PLLA was linked with chitin fibres by Dicyclohexylcarbodimide (DCC). The structures of the reinforced scaffold with and without linking were characterized by Scanning Electron Microscopy (SEM). The chemical characteristics of the chitin fibres with and without linking were evaluated by Fourier-transformed infrared (FTIR) spectroscopy. The mechanical performance during degradation in vitro was investigated. The results indicated that the nanohydroxyapatite/collagen/PLLA composite reinforced by chitin fibres with linking kept better mechanical properties than that of the composite without linking. These results denoted that the stronger interfacial bonding strength of the scaffold with linking could decrease the degradation rate in vitro. The reinforced composite with the link-treatment can be severed as a scaffold for bone tissue engineering, (c) 2005 Elsevier B.V. All rights reserved.; Tsinghau Univ
会议录出版者	ELSEVIER SCIENCE BV ; AMSTERDAM ; PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
语种	英语 ; 英语
内容类型	会议论文
源URL	[http://hdl.handle.net/123456789/18447]
专题	清华大学
推荐引用方式 GB/T 7714	Li, XM,Feng, QL,Cui, FZ. In vitro degradation of porous nano-hydroxyapatite/collagen/PLLA scaffold reinforced by chitin fibres[C]. 见:MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS, 2nd Asia Symnposium on Biomineralization, Beijing, PEOPLES R CHINA, Web of Science.

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