Materials Chemistry of Nanoultrasonic Biomedicine

CORC > 上海硅酸盐研究所 > 中国科学院上海硅酸盐研究所 > 高性能陶瓷和超微结构国家重点实验室 > 期刊论文

	Materials Chemistry of Nanoultrasonic Biomedicine
	Tang, Hailin 1; Zheng, Yuanyi 3; Chen, Yu 2
刊名	ADVANCED MATERIALS
	2017-03-14
卷号	29 期号:10
英文摘要	As a special cross-disciplinary research frontier, nanoultrasonic biomedicine refers to the design and synthesis of nanomaterials to solve some critical issues of ultrasound (US)-based biomedicine. The concept of nanoultrasonic biomedicine can also overcome the drawbacks of traditional microbubbles and promote the generation of novel US-based contrast agents or synergistic agents for US theranostics. Here, we discuss the recent developments of material chemistry in advancing the nanoultrasonic biomedicine for diverse US-based bio-applications. We initially introduce the design principles of novel nanoplatforms for serving the nanoultrasonic biomedicine, from the viewpoint of synthetic material chemistry. Based on these principles and diverse US-based bio-application backgrounds, the representative proof-of-concept paradigms on this topic are clarified in detail, including nanodroplet vaporization for intelligent/responsive US imaging, multifunctional nano-contrast agents for US-based multi-modality imaging, activatable synergistic agents for US-based therapy, US-triggered on-demand drug releasing, US-enhanced gene transfection, US-based synergistic therapy on combating the cancer and potential toxicity issue of screening various nanosystems suitable for nanoultrasonic biomedicine. It is highly expected that this novel nanoultrasonic biomedicine and corresponding high performance in US imaging and therapy can significantly promote the generation of new sub-discipline of US-based biomedicine by rationally integrating material chemistry and theranostic nanomedicine with clinical US-based biomedicine.
WOS标题词	Science & Technology ; Physical Sciences ; Technology
类目[WOS]	Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
研究领域[WOS]	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
关键词[WOS]	INTENSITY FOCUSED ULTRASOUND ; ACOUSTIC DROPLET VAPORIZATION ; TARGETED MICROBUBBLE DESTRUCTION ; MESOPOROUS SILICA NANOPARTICLES ; SUBMICRON PERFLUOROCARBON DROPLETS ; CONTRAST-ENHANCED ULTRASOUND ; MESENCHYMAL STEM-CELLS ; DRUG-DELIVERY SYSTEMS ; STIMULI-RESPONSIVE NANOCARRIERS ; HIGH-FREQUENCY ULTRASOUND
收录类别	SCI
语种	英语
WOS记录号	WOS:000396166800007
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/23465]
专题	上海硅酸盐研究所_高性能陶瓷和超微结构国家重点实验室_期刊论文
作者单位	1.Tongde Hosp Zhejiang Prov, Dept Diagnost Ultrasound, Hangzhou 310012, Zhejiang, Peoples R China 2.Chinese Acad Sci, State Key Lab High Performance Ceram & Superfine, Shanghai Inst Ceram, Shanghai 200050, Peoples R China 3.Shanghai Jiao Tong Univ, Affiliated Shanghai Peoples Hosp 6, Shanghai Inst Ultrasound Med, Shanghai 200233, Peoples R China
推荐引用方式 GB/T 7714	Tang, Hailin,Zheng, Yuanyi,Chen, Yu. Materials Chemistry of Nanoultrasonic Biomedicine[J]. ADVANCED MATERIALS,2017,29(10).
APA	Tang, Hailin,Zheng, Yuanyi,&Chen, Yu.(2017).Materials Chemistry of Nanoultrasonic Biomedicine.ADVANCED MATERIALS,29(10).
MLA	Tang, Hailin,et al."Materials Chemistry of Nanoultrasonic Biomedicine".ADVANCED MATERIALS 29.10(2017).