Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum
	Shi, Yan-Ni 1,2; Liu, Fang-Fang 1,3; Jacob, Melissa R.4; Li, Xing-Cong 4; Zhu, Hong-Tao 1,5; Wang, Dong1,5 ; Cheng, Rong-Rong1 ; Yang, Chong-Ren 1; Xu, Min 1; Zhang, Ying-Jun1,5
刊名	PLANTA MEDICA
	2017
卷号	83 期号:01-02 页码:143-150
关键词	Piper flaviflorum Piper sarmentosum Piperaceae amide alkaloids antifungal activity
英文摘要	Sixty-three amide alkaloids, including three new, piperflaviflorine A (1), piperflaviflorine B (2), and sarmentamide D (4), and two previously synthesized ones, (1E,3S)-1-cinnamoyl-3-hydroxypyrrolidine (3) and N-[7'-(4'-methoxyphenyl)ethyl]-2-methoxybenzamide (5), were isolated from the aerial parts of Piper flaviflorum and Piper sarmentosum. Their structures were elucidated by detailed spectroscopic analysis and, in case of 3, by single-crystal X-ray diffraction. Most of the isolates were tested for their antifungal and antibacterial activities. Ten amides (6-15) showed antifungal activity against Cryptococcus neoformans ATCC 90113 with IC50 values in the range between 4.7 and 20.0 mu g/mL.
类目[WOS]	Plant Sciences ; Chemistry, Medicinal ; Integrative & Complementary Medicine ; Pharmacology & Pharmacy
研究领域[WOS]	Plant Sciences ; Pharmacology & Pharmacy ; Integrative & Complementary Medicine
关键词[WOS]	CHEMICAL-CONSTITUENTS ; LONGUM ; ISOBUTYLAMIDES ; GLYCOSIDES ; WALLICHII ; FRUITS ; ASSAY ; BOND ; L.
收录类别	SCI
语种	英语
WOS记录号	WOS:000393182100018
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/41890]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Yunnan Univ Tradit Chinese Med, Kunming, Peoples R China 4.Univ Mississippi, Sch Pharm, Pharmaceut Sci Res Inst, Natl Ctr Nat Prod Res, University, MS 38677 USA 5.Chinese Acad Sci, Kunming Inst Bot, Yunnan Key Lab Nat Med Chem, Kunming, Peoples R China
推荐引用方式 GB/T 7714	Shi, Yan-Ni,Liu, Fang-Fang,Jacob, Melissa R.,et al. Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum[J]. PLANTA MEDICA,2017,83(01-02):143-150.
APA	Shi, Yan-Ni.,Liu, Fang-Fang.,Jacob, Melissa R..,Li, Xing-Cong.,Zhu, Hong-Tao.,...&Zhang, Ying-Jun.(2017).Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum.PLANTA MEDICA,83(01-02),143-150.
MLA	Shi, Yan-Ni,et al."Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum".PLANTA MEDICA 83.01-02(2017):143-150.