Fabrication of novel magnesium-matrix composites and their mechanical properties prior to and during in vitro degradation

CORC > 上海硅酸盐研究所 > 中国科学院上海硅酸盐研究所 > 生物材料与组织工程研究中心 > 期刊论文

	Fabrication of novel magnesium-matrix composites and their mechanical properties prior to and during in vitro degradation
	Dezfuli, Sina Naddaf 1; Leeflang, Sander 1; Huan, Zhiguang 2; Chang, Jiang 2; Zhou, Jie 1
刊名	JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
	2017-03-01
卷号	67 页码:74-86
关键词	Magnesium Magnesium-matrix composites Bredigite Degradation Mechanical properties
英文摘要	In our previous study, we developed Mg-matrix composites with bredigite as the reinforcing phase and achieved improved degradation resistance in comparison with Mg. However, the effects of materials processing method and process parameters on the mechanical behavior of the composites before and during degradation were still unknown. This research was aimed at determining the mechanical properties of Mg-bredigite composites prior to and during degradation. It was found that by optimizing the process parameters of Pressure Assisted Sintering (PAS), low-porosity Mg-bredigite composites with strong interfaces between homogeneously distributed bredigite particles and the Mg matrix could be fabricated. By reinforcing Mg with 20 vol% bredigite particles, the ultimate compressive strength and ductility of Mg increased by 67% and 111%, respectively. The in vitro degradation rate of the Mg-20% bredigite composite in a cell culture medium was 24 times lower than that of monolithic Mg. As a result of retarded degradation, the mechanical properties of the composite after 12 days of immersion in the cell culture medium were comparable to those of cortical bone. The encouraging results of this research warrant further investigations on the in vivo degradation behavior and mechanical properties of the composites.
WOS标题词	Science & Technology ; Technology
类目[WOS]	Engineering, Biomedical ; Materials Science, Biomaterials
研究领域[WOS]	Engineering ; Materials Science
关键词[WOS]	TISSUE CONDITION ; CANCELLOUS BONE ; TRABECULAR BONE ; ALLOYS ; BEHAVIOR ; SLIP ; MICROSTRUCTURE ; HYDROXYAPATITE ; STRENGTH ; HARDNESS
收录类别	SCI
语种	英语
WOS记录号	WOS:000392673900008
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/23409]
专题	上海硅酸盐研究所_生物材料与组织工程研究中心_期刊论文
作者单位	1.Delft Univ Technol, Dept Biomech Engn, NL-2628 CD Delft, Netherlands 2.Chinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China
推荐引用方式 GB/T 7714	Dezfuli, Sina Naddaf,Leeflang, Sander,Huan, Zhiguang,et al. Fabrication of novel magnesium-matrix composites and their mechanical properties prior to and during in vitro degradation[J]. JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS,2017,67:74-86.
APA	Dezfuli, Sina Naddaf,Leeflang, Sander,Huan, Zhiguang,Chang, Jiang,&Zhou, Jie.(2017).Fabrication of novel magnesium-matrix composites and their mechanical properties prior to and during in vitro degradation.JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS,67,74-86.
MLA	Dezfuli, Sina Naddaf,et al."Fabrication of novel magnesium-matrix composites and their mechanical properties prior to and during in vitro degradation".JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS 67(2017):74-86.