PI3K AKT and P-AKT levels in thin endometrium

	PI3K AKT and P-AKT levels in thin endometrium
	Le, A. W.; Shan, L. L.; Dai, X. Y.; Xiao, T. H.; Li, X. R.; Wang, Z. H.; Zhang, J.; Chen, X. Y.
刊名	GENETICS AND MOLECULAR RESEARCH
	2016
英文摘要	The aim of this study was to explore the expression of PI3K, AKT, and P-AKT, and to investigate the role ofPI3K/AKT signaling pathway in thin endometrium. We included 40 women treated in affiliated Shenzhen Nanshan People's Hospital of Guangdong Medical University for endometrial conditions between August 2013 and January 2015, 20 with a normal endometrium, and 20 with thin endometrium. The expression ofPI3K, AKT, and P-AKT was evaluated by the immunohistochemical S-P method. The expression of PI3K,AKT, and P-AKT proteins was significantly lower in the thin endometrium group than in the normalendometrium group (P < 0.05). The expression of PI3K and AKT was positively correlated with the expression of P-AKT. The expression of PI3K, AKT, and P-AKT proteins in the thin endometrium decreases during the proliferative phase, and this process could be associated with PI3K/AKT signaling.
收录类别	SCI
原文出处	http://geneticsmr.com/year2016/vol15-1/pdf/gmr7184.pdf
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/10739]
专题	深圳先进技术研究院_医药所
作者单位	GENETICS AND MOLECULAR RESEARCH
推荐引用方式 GB/T 7714	Le, A. W.,Shan, L. L.,Dai, X. Y.,et al. PI3K AKT and P-AKT levels in thin endometrium[J]. GENETICS AND MOLECULAR RESEARCH,2016.
APA	Le, A. W..,Shan, L. L..,Dai, X. Y..,Xiao, T. H..,Li, X. R..,...&Chen, X. Y..(2016).PI3K AKT and P-AKT levels in thin endometrium.GENETICS AND MOLECULAR RESEARCH.
MLA	Le, A. W.,et al."PI3K AKT and P-AKT levels in thin endometrium".GENETICS AND MOLECULAR RESEARCH (2016).