Strong correlation between early stage atherosclerosis and electromechanical coupling of aorta

	Strong correlation between early stage atherosclerosis and electromechanical coupling of aorta
	Liu, X. Y.; Yan, F.; Niu, L. L.; Chen, Q. N.; Zheng, H. R.; Li, J. Y.
刊名	NANOSCALE
	2016
英文摘要	Atherosclerosis is the underlying cause of cardiovascular diseases that are responsible for many deaths in the world, and the early diagnosis of atherosclerosis is highly desirable. The existing imaging methods, however, are not capable of detecting the early stage of atherosclerosis development due to their limited spatial resolution. Using piezoresponse force microscopy (PFM), we show that the piezoelectric responseof an aortic wall increases as atherosclerosis advances, while the stiffness of the aorta shows a less evidentcorrelation with atherosclerosis. Furthermore, we show that there is strong correlation between the coercive electric field necessary to switch the polarity of the artery and the development of atherosclerosis. Thus by measuring the electromechanical coupling of the aortic wall, it is possible to probe atherosclerosis at theearly stage of its development, not only improving the spatial resolution by orders of magnitude, but also providing comprehensive quantitative information on the biomechanical properties of the artery.
收录类别	SCI
原文出处	http://pubs.rsc.org/en/content/articlehtml/2016/nr/c5nr07398g
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/10456]
专题	深圳先进技术研究院_医工所
作者单位	NANOSCALE
推荐引用方式 GB/T 7714	Liu, X. Y.,Yan, F.,Niu, L. L.,et al. Strong correlation between early stage atherosclerosis and electromechanical coupling of aorta[J]. NANOSCALE,2016.
APA	Liu, X. Y.,Yan, F.,Niu, L. L.,Chen, Q. N.,Zheng, H. R.,&Li, J. Y..(2016).Strong correlation between early stage atherosclerosis and electromechanical coupling of aorta.NANOSCALE.
MLA	Liu, X. Y.,et al."Strong correlation between early stage atherosclerosis and electromechanical coupling of aorta".NANOSCALE (2016).