Numerical simulation of flow in curved coronary arteries with progressive amounts of stenosis using fluid-structure interaction modelling

	Numerical simulation of flow in curved coronary arteries with progressive amounts of stenosis using fluid-structure interaction modelling
	Guiying Liu; Jianhuang Wu; Wenhua Huang; Weidong Wu; Haonan Zhang; Kelvin K. L. Wong; Dhanjoo N. Ghista
刊名	JOURNAL OF MEDICAL IMAGING AND HEALTH INFORMATICS
	2014
英文摘要	The two-way fluid-structure interaction analysis (FSI) between the blood vessel wall and blood through elastic arteries with eccentric stenotic plaques was carried out in the ANSYS Mechanical and CFX modules based on the finite element method. The computational fluid dynamics simulation that is based on the pulsatile blood flow velocity and pressure at inlet and outlet of the artery allows us to study the fluid mechanical properties of blood through arteries with progressive amount of plaque growth. The hemodynamic analysis computation of average wall shear stress ((WSS) over bar) over the arterial surface, pressure drop (Delta P) between inlet and outlet of the artery, and von Mises stress (sigma(v)) at the throat of the stenosis is carried out for varying based on the degree of lumen stenosis. The results show that the values of ((WSS) over bar), Delta P and sigma(v) are in positive correlation with the narrowing of the lumen. Our FSI framework can effectively examine the influence of the variability in curvilinear arterial wall geometry on the blood flow characteristics. This study can be used to provide the biomedical engineering basis of the angiographic assessment of occlusion due to lesion development in curvilinear atherosclerotic coronary arteries.
收录类别	SCI
原文出处	http://chinesesites.library.ingentaconnect.com/content/asp/jmihi/2014/00000004/00000004/art00016?crawler=true&mimetype=application/pdf
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/5834]
专题	深圳先进技术研究院_医工所
作者单位	JOURNAL OF MEDICAL IMAGING AND HEALTH INFORMATICS
推荐引用方式 GB/T 7714	Guiying Liu,Jianhuang Wu,Wenhua Huang,et al. Numerical simulation of flow in curved coronary arteries with progressive amounts of stenosis using fluid-structure interaction modelling[J]. JOURNAL OF MEDICAL IMAGING AND HEALTH INFORMATICS,2014.
APA	Guiying Liu.,Jianhuang Wu.,Wenhua Huang.,Weidong Wu.,Haonan Zhang.,...&Dhanjoo N. Ghista.(2014).Numerical simulation of flow in curved coronary arteries with progressive amounts of stenosis using fluid-structure interaction modelling.JOURNAL OF MEDICAL IMAGING AND HEALTH INFORMATICS.
MLA	Guiying Liu,et al."Numerical simulation of flow in curved coronary arteries with progressive amounts of stenosis using fluid-structure interaction modelling".JOURNAL OF MEDICAL IMAGING AND HEALTH INFORMATICS (2014).