Blind-deconvolution optical-resolution photoacoustic microscopy in vivo

	Blind-deconvolution optical-resolution photoacoustic microscopy in vivo
	Jianhua Chen; Riqiang Lin; Huina Wang; Jing Meng; Hairong Zheng; Liang Song
刊名	OPTICS EXPRESS
	2013
英文摘要	Optical-resolution photoacoustic microscopy (OR-PAM) is becoming a vital tool for studying the microcirculation system in vivo. By increasing the numerical aperture of optical focusing, the lateral resolution of OR-PAM can be improved; however, the depth of focus and thus the imaging range will be sacrificed correspondingly. In this work, we report our development of blind-deconvolution optical-resolution photoacoustic microscopy (BD-PAM) that can provide a lateral resolution similar to 2-fold finer than that of conventional OR-PAM (3.04 vs. 5.78 mu m), without physically increasing the system's numerical aperture. The improvement achieved with BD-PAM is demonstrated by imaging graphene nanoparticles and the microvasculature of mice ears in vivo. Our results suggest that BD-PAM may become a valuable tool for many biomedical applications that require both fine spatial resolution and extended depth of focus.
收录类别	SCI
原文出处	https://www.osapublishing.org/oe/abstract.cfm?uri=oe-21-6-7316
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/4818]
专题	深圳先进技术研究院_医工所
作者单位	OPTICS EXPRESS
推荐引用方式 GB/T 7714	Jianhua Chen,Riqiang Lin,Huina Wang,et al. Blind-deconvolution optical-resolution photoacoustic microscopy in vivo[J]. OPTICS EXPRESS,2013.
APA	Jianhua Chen,Riqiang Lin,Huina Wang,Jing Meng,Hairong Zheng,&Liang Song.(2013).Blind-deconvolution optical-resolution photoacoustic microscopy in vivo.OPTICS EXPRESS.
MLA	Jianhua Chen,et al."Blind-deconvolution optical-resolution photoacoustic microscopy in vivo".OPTICS EXPRESS (2013).