Programmable manipulation of microbubbles in microfluidic systems with surface acoustic wave

	Programmable manipulation of microbubbles in microfluidic systems with surface acoustic wave
	Meng, Long; Cai, Feiyan; Niu, Lili; Li, Yanming; Zheng, Hairong
刊名	The Journal of the Acoustical Society of America
	2012
英文摘要	Programmable microfluidic systems for bioparticles manipulation that could enable automated biological analysis and diagnostics have the potential to revolutionize a wide range of applications in life sciences research, clinical diagnostics, and drug discovery. Several methods such as those based on hydrodynamic force, magnetic tweezers, and dielectrophoresis can manipulate the movement of the bioparticles successfully. However, these methods must be constructed the flow structure, magnetic wire, and electrode in the microchannel respectively, which not only limits the flexibility of manipulation but also makes the sample more likely to be contaminated. In this paper, a programmable microfluidic device is developed to manipulate the microbubbles along an arbitrary trajectory in the microchannel without any structure by introducing phase-shifts to a planar standing surface acoustic wave field. The microbubbles can be transported in a square trajectory, circular trajectory and even helix trajectory via adjusting the relative phase between the excitation signals controlled by LabVIEW program. The results reveal that the microbubbles can be transported over a predetermined distance continuously until they reach the targeted locations. This acoustic programmable microfluidic device would have potential applications on drug screening, cell studies, and other biomedical applications. Programmable manipulation of microbubbles in microfluidic systems with surface acoustic wave.. Available from: http://www.researchgate.net/publication/224035526_Programmable_manipulation_of_microbubbles_in_microfluidic_systems_with_surface_acoustic_wave [accessed Jun 4, 2015].
收录类别	其他
原文出处	http://scitation.aip.org/content/asa/journal/jasa/131/4/10.1121/1.4708499
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/3957]
专题	深圳先进技术研究院_医工所
作者单位	The Journal of the Acoustical Society of America
推荐引用方式 GB/T 7714	Meng, Long,Cai, Feiyan,Niu, Lili,et al. Programmable manipulation of microbubbles in microfluidic systems with surface acoustic wave[J]. The Journal of the Acoustical Society of America,2012.
APA	Meng, Long,Cai, Feiyan,Niu, Lili,Li, Yanming,&Zheng, Hairong.(2012).Programmable manipulation of microbubbles in microfluidic systems with surface acoustic wave.The Journal of the Acoustical Society of America.
MLA	Meng, Long,et al."Programmable manipulation of microbubbles in microfluidic systems with surface acoustic wave".The Journal of the Acoustical Society of America (2012).