Assessment of Carotid Stenosis Using Three-Dimensional T2-Weighted Dark Blood Imaging：Initial Experience

	Assessment of Carotid Stenosis Using Three-Dimensional T2-Weighted Dark Blood Imaging：Initial Experience
	Georgeta Mihai; Marshall W. Winner; Subha V. Raman; MSEE; Sanjay Rajagopalan; Orlando P. Simonetti; Yiu-Cho Chung
刊名	JOURNAL OF MAGNETIC RESONANCE IMAGING
	2012
英文摘要	Purpose: To evaluate the use of a T2-weighted SPACE sequence (T2w-SPACE) to assess carotid stenosis via several methods and compare its performance with contrast-enhanced magnetic resonance angiography (ceMRA). Materials and Methods: Fifteen patients with carotid atherosclerosis underwent dark blood (DB)-MRI using a 3D turbo spin echo with variable flip angles sequence (T2w-SPACE) and ceMRA. Images were coregistered and evaluated by two observers. Comparisons were made for luminal diameter, luminal area, degree of luminal stenosis (NAS-CET: North American Symptomatic Endarterectomy Trial; ECST: European Carotid Surgery Trial, and area stenosis), and vessel wall area. Degree of NASCET stenosis was clinically classified as mild (<50%), moderate (50%-69%), or severe (>69%). Results: Excellent agreement was seen between ceMRA and T2w-SPACE and between observers for assessment of lumen diameter, lumen area, vessel wall area, and degree of NASCET stenosis (r > 0.80, P < 0.001). ECST stenosis was consistently higher than NASCET stenosis (48 +/- 14% vs. 24 +/- 22%, P < 0.001). Area stenosis (72 +/- 2%) was significantly higher (P < 0.001) than both ESCT and NASCET stenosis. Conclusion: DB-MRI of carotid arteries using T2w-SPACE is clinically feasible. It provides accurate measurements of lumen size and degree of stenosis in comparison with ceMRA and offers a more reproducible measure of ECST stenosis than ceMRA.
收录类别	SCI
原文出处	http://onlinelibrary.wiley.com/doi/10.1002/jmri.22839/pdf
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/3953]
专题	深圳先进技术研究院_医工所
作者单位	JOURNAL OF MAGNETIC RESONANCE IMAGING
推荐引用方式 GB/T 7714	Georgeta Mihai,Marshall W. Winner,Subha V. Raman,等. Assessment of Carotid Stenosis Using Three-Dimensional T2-Weighted Dark Blood Imaging：Initial Experience[J]. JOURNAL OF MAGNETIC RESONANCE IMAGING,2012.
APA	Georgeta Mihai.,Marshall W. Winner.,Subha V. Raman.,MSEE.,Sanjay Rajagopalan.,...&Yiu-Cho Chung.(2012).Assessment of Carotid Stenosis Using Three-Dimensional T2-Weighted Dark Blood Imaging：Initial Experience.JOURNAL OF MAGNETIC RESONANCE IMAGING.
MLA	Georgeta Mihai,et al."Assessment of Carotid Stenosis Using Three-Dimensional T2-Weighted Dark Blood Imaging：Initial Experience".JOURNAL OF MAGNETIC RESONANCE IMAGING (2012).