Comparative genomics reveals insights into avian genome evolution and adaptation
Zhang GJ[*]1,2; Li C1,3; Lee C5,6; Storz JF7; Fan Y9; Li QY1,3; Li B1; Larkin DM4
刊名Science
2014
卷号346期号:6215页码:1311-1320
通讯作者zhanggj@genomics.cn
合作状况其它
英文摘要Birds are the most species-rich class of tetrapod vertebrates and have wide relevance across many research fields. We explored bird macroevolution using full genomes from 48 avian species representing all major extant clades. The avian genome is principally characterized by its constrained size, which predominantly arose because of lineage-specific erosion of repetitive elements, large segmental deletions, and gene loss. Avian genomes furthermore show a remarkably high degree of evolutionary stasis at the levels of nucleotide sequence, gene synteny, and chromosomal structure. Despite this pattern of conservation, we detected many non-neutral evolutionary changes in protein-coding genes and noncoding regions. These analyses reveal that pan-avian genomic diversity covaries with adaptations to different lifestyles and convergent evolution of traits
收录类别SCI
语种英语
内容类型期刊论文
源URL[http://159.226.149.26:8080/handle/152453/9566]  
专题昆明动物研究所_重大疾病机理的遗传学
昆明动物研究所_动物模型与人类重大疾病机理重点实验室
作者单位1.China National GeneBank, Beijing Genomics Institute (BGI)–Shenzhen, Shenzhen, 518083, China
2.Centre for Social Evolution, Department of Biology, Universitetsparken 15, University of Copenhagen, DK-2100 Copenhagen, Denmark
3.Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, 1350 Copenhagen, Denmark
4.Royal Veterinary College, University of London, London, UK
5.Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul 151-742, Republic of Korea
6.Cho and Kim Genomics, Seoul National University Research Park, Seoul 151-919, Republic of Korea
7.School of Biological Sciences, University of Nebraska, Lincoln, NE 68588, USA
8.Centro de Investigación en Ciencias del Mar y Limnología (CIMAR)/Centro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), Universidade do Porto, Rua dos Bragas, 177, 4050-123 Porto, Portugal.
9.Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan 650223, China
推荐引用方式
GB/T 7714
Zhang GJ[*],Li C,Lee C,et al. Comparative genomics reveals insights into avian genome evolution and adaptation[J]. Science,2014,346(6215):1311-1320.
APA Zhang GJ[*].,Li C.,Lee C.,Storz JF.,Fan Y.,...&Larkin DM.(2014).Comparative genomics reveals insights into avian genome evolution and adaptation.Science,346(6215),1311-1320.
MLA Zhang GJ[*],et al."Comparative genomics reveals insights into avian genome evolution and adaptation".Science 346.6215(2014):1311-1320.
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