Hippo pathway in mammary gland development and breast cancer

CORC > 昆明动物研究所 > 昆明动物研究所 > 动物模型与人类重大疾病机理重点实验室 > 肿瘤生物学

	Hippo pathway in mammary gland development and breast cancer
	Shi PG 1,2; Feng J[]3; Chen CS[]1
刊名	ACTA BIOCHIMICA ET BIOPHYSICA SINICA
	2015
卷号	47 期号:1 页码:53-59
关键词	Hippo pathway YAP TAZ mammary gland development breast cancer
通讯作者	fengjing8801530@163.com ; chenc@mail.kiz.ac.cn
合作状况	其它
英文摘要	Accumulated evidence suggests that the Hippo signaling pathway plays crucial roles in mammary gland development and breast cancer. Key components of the Hippo pathway regulate breast epithelial cell proliferation, migration, invasion, and stemness. Additionally, the Hippo pathway regulates breast tumor growth, metastasis, and drug resistance. It is expected that the Hippo pathway will provide novel therapeutic targets for breast cancer. This review will discuss and summarize the roles of several core components of the Hippo pathway in mammary gland development and breast cancer.
收录类别	SCI
资助信息	This work was supported by the grants from the Strategic Priority Research Program of the Chinese Academy of Sciences, Stem Cell and Regenerative Medicine Research (No. XDA01040406) and the National Natural Science Foundation of China (Nos. 81072162, 81120108019, and U1132605).
语种	英语
公开日期	2015-02-06
内容类型	期刊论文
源URL	[http://159.226.149.42:8088/handle/152453/8248]
专题	昆明动物研究所_肿瘤生物学昆明动物研究所_动物模型与人类重大疾病机理重点实验室
作者单位	1.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Chinese Academy of Sciences, Kunming Institute of Zoology, Kunming 650223, China 2.University of Chinese Academy of Sciences, Beijing 100049, China 3.Department of laboratory medicine & Central Laboratory, South Medical University Affiliated Fengxian Hospital, Shanghai 201499, China
推荐引用方式 GB/T 7714	Shi PG,Feng J[],Chen CS[]. Hippo pathway in mammary gland development and breast cancer[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2015,47(1):53-59.
APA	Shi PG,Feng J[],&Chen CS[].(2015).Hippo pathway in mammary gland development and breast cancer.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,47(1),53-59.
MLA	Shi PG,et al."Hippo pathway in mammary gland development and breast cancer".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 47.1(2015):53-59.