A new method for piercing the tentorium cerebelli for implanting fragile electrodes into the brain stem in the rhesus monkey (Macaca mulatta)

CORC > 昆明动物研究所 > 昆明动物研究所 > 动物模型与人类重大疾病机理重点实验室 > 神经系统编码

	A new method for piercing the tentorium cerebelli for implanting fragile electrodes into the brain stem in the rhesus monkey (Macaca mulatta)
	Wu J 1; Wang WC 1,5; Rizak JD 1,5; Wang ZB 1; Wang JH 1; Feng XL 1; Dong JR 1; Li L 4; Liu L 4; Xu LQ 4
刊名	JOURNAL OF NEUROPHYSIOLOGY
	2014
卷号	111 期号:5 页码:1027-1032
关键词	dura mater tentorium cerebelli piercing fragile electrodes Macaca mulatta
通讯作者	yangsc@mail.kiz.ac.cn
合作状况	其它
英文摘要	Recent developments in neuron recording techniques include the invention of some fragile electrodes. The fragility of these electrodes impedes their successful use in deep brain recordings because it is difficult to penetrate the electrodes through the dura mater, especially the tentorium cerebelli (TC) enclosing the cerebellum and brain stem. This paper reports a new method to pierce the TC for inserting fragile electrodes into the inferior colliculus of rhesus monkeys. Briefly, a unique tool kit, consisting of needles with sharp tips, a guide tube and an "impactor," was used in a multistep protocol to pierce the TC. The impactor provided a brief force that quickly thrusts the needles through the meninges without causing significant damage to the brain tissue under the TC. Using this novel approach, tetrodes were successfully implanted into the inferior colliculus of a rhesus monkey and neuronal discharge signals were recorded. This method, which is simple, convenient and economical, allows neurophysiologists to study the electrophysiological characteristics of deep brain structures under the TC with advanced, albeit fragile, electrodes
收录类别	SCI
资助信息	This research was supported by the Strategic Priority Research Pro- gram of the Chinese Academy of Science XDB02020000; 973 program 2012CB825500, 2012CBA01304 and 2011CB707800; the 863 program 2012AA020701, KSCX2-EW-J-23 and KSCX2-EW-R-11; and the National Science Foundation of China 91332120, 31271167, 31070963, 31271168, 81271495 and 31070965.
语种	英语
WOS记录号	WOS:000335669900014
公开日期	2014-10-24
内容类型	期刊论文
源URL	[http://159.226.149.42:8088/handle/152453/8141]
专题	昆明动物研究所_神经系统编码昆明动物研究所_动物模型与人类重大疾病机理重点实验室昆明动物研究所_中国科学院昆明灵长类研究中心
作者单位	1.Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, P. R. China 2.Kunming Primate Research Center, Kunming Institute of Zoology, Chinese Academy of Science, Kunming, Yunnan, China 3.Yunnan Key Laboratory of Primate Biomedical Research, Kunming, Yunnan, China 4.Medical Image Office, Kunming General Hospital of PLA, Yunnan, P. R. China 5.University of Chinese Academy of Sciences, Beijing, P. R. China
推荐引用方式 GB/T 7714	Wu J,Wang WC,Rizak JD,et al. A new method for piercing the tentorium cerebelli for implanting fragile electrodes into the brain stem in the rhesus monkey (Macaca mulatta)[J]. JOURNAL OF NEUROPHYSIOLOGY,2014,111(5):1027-1032.
APA	Wu J.,Wang WC.,Rizak JD.,Wang ZB.,Wang JH.,...&Hu XT.(2014).A new method for piercing the tentorium cerebelli for implanting fragile electrodes into the brain stem in the rhesus monkey (Macaca mulatta).JOURNAL OF NEUROPHYSIOLOGY,111(5),1027-1032.
MLA	Wu J,et al."A new method for piercing the tentorium cerebelli for implanting fragile electrodes into the brain stem in the rhesus monkey (Macaca mulatta)".JOURNAL OF NEUROPHYSIOLOGY 111.5(2014):1027-1032.