A folding "framework structure" of Tetrahymena group I intron | |
Zhang X1,2; Guo C1; Zhang W1,3; Cao HA1; Xie HZ1; Wang K1; Liu CQ[*]1,4,5 | |
刊名 | JOURNAL OF THEORETICAL BIOLOGY
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2010 | |
卷号 | 267期号:4页码:495-501 |
关键词 | Ribozyme Dynamic extended folding Splice site RNA secondary structure |
通讯作者 | liucq@ynu.edu.cn |
合作状况 | 其它 |
英文摘要 | We have published the dynamic extended folding (DEF) method which is a RNA secondary structure prediction approach to simulate the in vivo RNA co-transcriptional folding process In order to verify the reliability of the method we selected the X-ray-determined Tetrahymena group I intron as a sample to construct the framework of its folding secondary structure Our prediction coincides well with the secondary structure predicted by T R. Cech and the X-ray diffraction crystal structure determined by Lehnert V Our results show that the DEF framework structure of Tetrahymena group I intron reflects its function sites in a concise and straightforward manner and the scope of the simulation was expanded |
收录类别 | SCI |
资助信息 | This work is granted by the Natural Science Fund of China (Nos. 90303018, 90208018 and 30971454). |
语种 | 英语 |
公开日期 | 2010-12-17 |
内容类型 | 期刊论文 |
源URL | [http://159.226.149.42:8088/handle/353002/6545] ![]() |
专题 | 昆明动物研究所_其他 |
作者单位 | 1.Modern Biological Research Center, Yunnan University, Kunming 650091, China 2.Department of Food Science and Nutrition, Zhejiang University, Hangzhou 310029, China 3.Department of Cell Biology and Genetics, Kunming Medical College, Kunming 650031, China 4.Kunming Institute of Zoology, Chinese Academy of Science, Kunming 650223, China 5.Center of Theoretical Biology, Peking University, Beijing 100871, China |
推荐引用方式 GB/T 7714 | Zhang X,Guo C,Zhang W,et al. A folding "framework structure" of Tetrahymena group I intron[J]. JOURNAL OF THEORETICAL BIOLOGY,2010,267(4):495-501. |
APA | Zhang X.,Guo C.,Zhang W.,Cao HA.,Xie HZ.,...&Liu CQ[*].(2010).A folding "framework structure" of Tetrahymena group I intron.JOURNAL OF THEORETICAL BIOLOGY,267(4),495-501. |
MLA | Zhang X,et al."A folding "framework structure" of Tetrahymena group I intron".JOURNAL OF THEORETICAL BIOLOGY 267.4(2010):495-501. |
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