Terpenoids and their anti-HIV-1 activities from Excoecaria acerifolia

CORC > 昆明动物研究所 > 昆明动物研究所 > 动物模型与人类重大疾病机理重点实验室 > 分子免疫药理学

	Terpenoids and their anti-HIV-1 activities from Excoecaria acerifolia
	Huang SZ 1,4; Zhang X 3; Ma QY 1,4; Zheng YT 3; Xu FQ 2; Peng H 2; Dai HF 1,4; Zhou J[]2; Zhao YX[]1,4
刊名	FITOTERAPIA
	2013
卷号	91 期号:X 页码:224-230
关键词	Excoecaria acerifolia Euphorbiaceae Anti-HIV Diterpenoid Triterpenoid
通讯作者	junzhou3264@126.com ; zhaoyouxing@itbb.org.cn
合作状况	其它
英文摘要	Five new diterpenoids named excocarinols A-E (1-5) including three pimaranes, one cleistanthane, and one nor-beyerane, together with nine known compounds, were isolated from the EtOAc extract of the Chinese ethnodrug Gua-jing-ban (Excoecaria acerifolia Didr.). Their structures were elucidated by the analysis of spectroscopic data including 1D, 2D NMR and HR-MS. The anti-HIV-1 bioassay on the diterpenoids showed that excocarinol A (1) exhibited moderate anti-HIV-1 activity with EC50 5.58 mu M and SI (Selection Index) over 112.71.
收录类别	SCI
资助信息	This work wasfinancially supported by the Special Fund for Agro-scientific Research in the Public Interest (201303117), the National Support Science and Technology Subject (2013BAI11B04), and the Fundamental Scientific Research Funds for CATAS (1630052013001; ITBB110301).
语种	英语
WOS记录号	WOS:000327574300033
公开日期	2014-10-22
内容类型	期刊论文
源URL	[http://159.226.149.42:8088/handle/152453/8124]
专题	昆明动物研究所_分子免疫药理学昆明动物研究所_动物模型与人类重大疾病机理重点实验室
作者单位	1.Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, People's Republic of China 2.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China 3.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Science & Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, People's Republic of China 4.Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Haikou 571101, People's Republic of China
推荐引用方式 GB/T 7714	Huang SZ,Zhang X,Ma QY,et al. Terpenoids and their anti-HIV-1 activities from Excoecaria acerifolia[J]. FITOTERAPIA,2013,91(X):224-230.
APA	Huang SZ.,Zhang X.,Ma QY.,Zheng YT.,Xu FQ.,...&Zhao YX[*].(2013).Terpenoids and their anti-HIV-1 activities from Excoecaria acerifolia.FITOTERAPIA,91(X),224-230.
MLA	Huang SZ,et al."Terpenoids and their anti-HIV-1 activities from Excoecaria acerifolia".FITOTERAPIA 91.X(2013):224-230.