Recent Advances in Conjugated Polymer Materials for Disease Diagnosis

	Recent Advances in Conjugated Polymer Materials for Disease Diagnosis
	Lv, Fengting 1; Qiu, Tian 2,3; Liu, Libing 1; Ying, Jianming 2,3; Wang, Shu 1
刊名	SMALL
	2016-02-10
卷号	12 期号:6 页码:696-705
关键词	conjugated polymers optical amplification sensing diagnosis
英文摘要	The extraordinary optical amplification and light-harvesting properties of conjugated polymers impart sensing systems with higher sensitivity, which meets the primary demands of early cancer diagnosis. Recent advances in the detection of DNA methylation and mutation with polyfluorene derivatives based fluorescence resonance energy transfer (FRET) as a means to modulate fluorescent responses attest to the great promise of conjugated polymers as powerful tools for the clinical diagnosis of diseases. To facilitate the ever-changing needs of diagnosis, the development of detection approaches and FRET signal analysis are highlighted in this review. Due to their exceptional brightness, excellent photostability, and low or absent toxicity, conjugated polymers are verified as superior materials for in-vivo imaging, and provide feasibility for future clinical molecular-imaging applications. The integration of conjugated polymers with clinical research has shown profound effects on diagnosis for the early detection of disease-related biomarkers, as well as in-vivo imaging, which leads to a multidisciplinary scientific field with perspectives in both basic research and application issues.
收录类别	SCI
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/35811]
专题	化学研究所_有机固体实验室
作者单位	1.Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China 2.Chinese Acad Med Sci, Canc Hosp, Dept Pathol, Beijing 100021, Peoples R China 3.Peking Union Med Coll, Beijing 100021, Peoples R China
推荐引用方式 GB/T 7714	Lv, Fengting,Qiu, Tian,Liu, Libing,et al. Recent Advances in Conjugated Polymer Materials for Disease Diagnosis[J]. SMALL,2016,12(6):696-705.
APA	Lv, Fengting,Qiu, Tian,Liu, Libing,Ying, Jianming,&Wang, Shu.(2016).Recent Advances in Conjugated Polymer Materials for Disease Diagnosis.SMALL,12(6),696-705.
MLA	Lv, Fengting,et al."Recent Advances in Conjugated Polymer Materials for Disease Diagnosis".SMALL 12.6(2016):696-705.