Binding-Directed Energy Transfer of Conjugated Polymer Materials for Dual-Color Imaging of Cell Membrane

	Binding-Directed Energy Transfer of Conjugated Polymer Materials for Dual-Color Imaging of Cell Membrane
	Cui, Qianling 1; Wang, Xiaoyu 1,2; Yang, Yu 1; Li, Shengliang 2; Li, Lidong 1; Wang, Shu 2
刊名	CHEMISTRY OF MATERIALS
	2016-07-12
卷号	28 期号:13 页码:4661-4669
英文摘要	Binding of biomolecules or probes to the plasma membrane is of great importance for investigations of cell morphology and various biological processes. Herein, a water-soluble conjugated polymer is designed as a membrane probe. The probe shows a strong affinity toward lipid membranes owing to the high charge density from abundant imidazolium moieties together with the moderate rigidity and hydrophobicity derived from the conjugated backbone. Upon binding with a membrane, the interchain FRET of the probe was substantially enhanced, which resulted in the emission of both blue and red fluorescence. This is favorable for dual-color imaging. Finally, cellular experiments demonstrate the excellent performance of this macromolecular probe on stable binding with cell membranes without the appearance of cell endocytocysis even after a long retention time.
收录类别	SCI
语种	英语
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/35613]
专题	化学研究所_有机固体实验室
作者单位	1.Univ Sci & Technol Beijing, Sch Mat Sci & Engn, State Key Lab Adv Met & Mat, Beijing 100083, Peoples R China 2.Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Cui, Qianling,Wang, Xiaoyu,Yang, Yu,et al. Binding-Directed Energy Transfer of Conjugated Polymer Materials for Dual-Color Imaging of Cell Membrane[J]. CHEMISTRY OF MATERIALS,2016,28(13):4661-4669.
APA	Cui, Qianling,Wang, Xiaoyu,Yang, Yu,Li, Shengliang,Li, Lidong,&Wang, Shu.(2016).Binding-Directed Energy Transfer of Conjugated Polymer Materials for Dual-Color Imaging of Cell Membrane.CHEMISTRY OF MATERIALS,28(13),4661-4669.
MLA	Cui, Qianling,et al."Binding-Directed Energy Transfer of Conjugated Polymer Materials for Dual-Color Imaging of Cell Membrane".CHEMISTRY OF MATERIALS 28.13(2016):4661-4669.