Copper-Catalyzed Asymmetric Three-Component Borylstannation: Enantioselective Formation of C-Sn Bond

	Copper-Catalyzed Asymmetric Three-Component Borylstannation: Enantioselective Formation of C-Sn Bond
	Jia, Tao; Cao, Peng; Wang, Ding; Lou, Yazhou; Liao, Jian
刊名	CHEMISTRY-A EUROPEAN JOURNAL
	2015
卷号	21 期号:13 页码:4918-4922
关键词	CROSS-COUPLING REACTIONS TERMINAL ALKENES COPPER(I)-CATALYZED REACTION PALLADIUM CATALYSIS DYNAMIC RESOLUTION ARYLBORONIC ACIDS BORONIC ESTERS ARYL HALIDES DIBORATION STANNANES
通讯作者	Liao, J (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Nat Prod Res Ctr, Chengdu 610041, Peoples R China.
产权排序	1
合作状况	国内
英文摘要	In summary, a first copper-catalyzed synthesis of alpha-aryl-beta-borylstannane compounds was accomplished through three-component borylstannation of aryl-substituted alkenes. In the exploration of an asymmetric variant, chiral sulfinylphosphine ligands proved advantageous in controlling stereochemistry of B-Cu addition and in promoting transmetalation of enantioenriched alkyl-Cu species. The stereochemical outcome supported a sequential syn-borylcupration and configuration-retentive transmetalation mechanism. Moreover, alpha-chiral beta-borylstannanes were easily transformed into a diverse array of secondary alkylstannanes and triarylethane with high enantiomeric purity. The applications of chiral sulfinylphosphine ligands to other tandem Cu-B addition reactions are currently under investigation in our group.
学科主题	Chemistry
类目[WOS]	Chemistry, Multidisciplinary
收录类别	SCI
语种	英语
内容类型	期刊论文
源URL	[http://210.75.237.14/handle/351003/27593]
专题	成都生物研究所_天然产物研究
推荐引用方式 GB/T 7714	Jia, Tao,Cao, Peng,Wang, Ding,et al. Copper-Catalyzed Asymmetric Three-Component Borylstannation: Enantioselective Formation of C-Sn Bond[J]. CHEMISTRY-A EUROPEAN JOURNAL,2015,21(13):4918-4922.
APA	Jia, Tao,Cao, Peng,Wang, Ding,Lou, Yazhou,&Liao, Jian.(2015).Copper-Catalyzed Asymmetric Three-Component Borylstannation: Enantioselective Formation of C-Sn Bond.CHEMISTRY-A EUROPEAN JOURNAL,21(13),4918-4922.
MLA	Jia, Tao,et al."Copper-Catalyzed Asymmetric Three-Component Borylstannation: Enantioselective Formation of C-Sn Bond".CHEMISTRY-A EUROPEAN JOURNAL 21.13(2015):4918-4922.