| 题名 | 生物成像新型全固态激光技术 |
| 作者 | 喻乾桓 |
| 学位类别 | 硕士 |
| 答辩日期 | 2015 |
| 授予单位 | 中国科学院上海光学精密机械研究所 |
| 导师 | 陈卫标 |
| 关键词 | 生物成像，Nd:YAG，KTP，光学参量振荡器，相位匹配 |
| 其他题名 | New all-solid-state laser technology for biomedical imaging |
| 中文摘要 | 全固态光学参量振荡器具有效率高、体积小以及结构紧凑等特点，在激光雷达、遥感、环境监测、以及生物医疗等方面有着非常重要应用价值和使用前景。从1965年第一台光学参量振荡器被Giordmaine和Miller报道以来，利用非线性效应的光学参量振荡器如今已成为获得红外激光的一种非常有效的途径。 由于最新研究表明1.73 μm波段激光可以用于生物医疗上的光声成像，本文主要围绕利用1064 nm激光器作为泵浦的光学参量振荡器，对于1.73 μm光学参量振荡器的基本理论及实验展开了系统的研究。本文首先介绍了该波段激光的应用背景和使用价值。讨论了几种产生1.73 μm激光的主要方法，详细论述了光学参量振荡器的发展现状和发展趋势，并对光学参量振荡器中几种常见的相位匹配技术做了基本介绍。结合实验采用的单通单谐振的腔型结构对激光器的结构参数进行了数值分析，为后续实验设计打下理论基础。在1.73 μm的光学参量振荡器实验中，我们利用实验室自行搭建的双端泵浦Nd:YAG 1064 nm激光器作为基频光源，通过腔外光学参量振荡器成功获得1.56 W的1729.4 nm的信号光作为输出。最后获得了单脉冲能量最高超过3 mJ，脉宽11.22 ns的脉冲。脉冲重复频率为500 Hz，输出激光谱宽为0.1 nm。在完成对1.73 μm KTP-OPO激光器桌面验证试验后，我们还搭建了一台性能稳定的工程样机用于生物成像实验。经测试样机功率稳定性良好，两小时内连续测量功率抖动不超过0.6%。目前工程样机整体性能稳定，已成功应用于生物组织的光声成像，成像效果良好。 |
| 英文摘要 | All-solid-state laser characterized as stable performance, small size, compact structure and high efficiency is very promising in many applications such as laser radar, remote sensing, environment monitoring, biomedical treatment, etc. Optical parametric oscillator has been an effective method to obtain infrared laser since first optical parametric oscillator was reported by Giordmain and Miller in 1965. Recent research has revealed that laser emitting around 1.73μm can been applied in photoacoustic imaging for medical treatment. In this thesis we focused on optical parametrical oscillator based on Nd:YAG laser pumping KTP crystal. Both theory and experiments of 1.73μm optical parametrical oscillator have been systemically studied in the article. Firstly we briefly introduced the application value of this laser and several ways leading to the laser emitting around 1.73μm. Following with the introduction of current situation and the trend about the development of OPO, the principle of phase match was stated. According to practical situation of single-pass resonator, we analyzed several kinds of structure parameters by simulation, which providing a theoretical foundation for follow-up experiments. In the experiment of 1.73 μm OPO, we adopted homemade double-end pumping Nd:YAG laser as fundamental laser. A maximum output power of 1.56 W at 1729.4 nm was obtained. The pulse with pulse duration of 11.22 ns exceeds 3 mJ at 500 Hz repetition rate. The linewidth of the laser is about 0.1 nm. Moreover an engineering prototype has been made with stable performance. The output pulse energy fluctuation supervised by power meter of 1.73 μm is less than 0.6% during 2 hours operating period. Currently this prototype has been applied into the biomedical imaging experiments successfully. |
| 语种 | 中文 |
| 内容类型 | 学位论文 |
| 源URL | [http://ir.siom.ac.cn/handle/181231/16891]  |
| 专题 | 上海光学精密机械研究所_学位论文 |
| 推荐引用方式 GB/T 7714 | 喻乾桓. 生物成像新型全固态激光技术[D]. 中国科学院上海光学精密机械研究所. 2015. |
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