Fabrication of uniform alginate-agarose microcapsules loading FeSO4 using water-oil-water-oil multiple emulsions system combined with premix membrane emulsification technique

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	Fabrication of uniform alginate-agarose microcapsules loading FeSO4 using water-oil-water-oil multiple emulsions system combined with premix membrane emulsification technique
	Zhang, Bo 1,2; Yang, Tingyuan 1; Wang, Qibao 2; Zhang, Guifeng 1; Huo, Junsheng 3; Huang, Jian 3; Wang, Lianyan 1
刊名	COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
	2016-06-05
卷号	498 期号:JUNE 页码:128-138
关键词	Premix membrane emulsification Water-oil-water-oil multiple emulsion system Alginate Agarose Microcapsules FeSO4 encapsulation
ISSN号	0927-7757
英文摘要	In this study, the uniform alginate-agarose microcapsules entrapping FeSO4 were successfully fabricated by premix membrane emulsification technique combined with ionic crosslinking solidification method. It was the first time to employ four phase emulsions system of W-1/O-1/W-2/O-2 for encapsulating FeSO4 into alginate-agarose microcapsules. We systematically investigated how the preparation parameters including type of oil phase and emulsifier, concentrations of alginate and agarose and volume ratios between oil and water phase influenced the stability of emulsions, the morphology and size distributions of microcapsules and loading efficiency of FeSO4. We found that the stability of emulsion was improved with the increase of viscosity and density of outer oil phase (O-2), the concentration of emulsifier as well as the volume ratio between inner water phase and inner oil phase (W-1/O-1) within a certain range. Besides, loading capacity of Fe2+ in alginate/agarose microcapsules presented an increase tendency with the decrease of the volume ratio between external water phase (W-2) and primary emulsion [W-2/(O-1/W-1) (v/v)], and also decreased with the concentration of W-2.
WOS标题词	Science & Technology ; Physical Sciences
类目[WOS]	Chemistry, Physical
研究领域[WOS]	Chemistry
关键词[WOS]	INVERSION TEMPERATURE METHOD ; ATOMIC-FORCE MICROSCOPY ; IRON-DEFICIENCY ANEMIA ; W/O NANO-EMULSIONS ; MECHANICAL-PROPERTIES ; FERROUS SULFATE ; MICROSPHERES ; PARTICLES ; MICROPARTICLES ; ENCAPSULATION
收录类别	SCI
语种	英语
WOS记录号	WOS:000375165700016
内容类型	期刊论文
源URL	[http://ir.ipe.ac.cn/handle/122111/21038]
专题	过程工程研究所_生化工程国家重点实验室
作者单位	1.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.China Univ Ming & Technol, Sch Chem & Environm Engn, Beijing 100083, Peoples R China 3.Chinese Ctr Dis Control & Prevent, Natl Inst Nutr & Hlth, Beijing 100050, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Bo,Yang, Tingyuan,Wang, Qibao,et al. Fabrication of uniform alginate-agarose microcapsules loading FeSO4 using water-oil-water-oil multiple emulsions system combined with premix membrane emulsification technique[J]. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,2016,498(JUNE):128-138.
APA	Zhang, Bo.,Yang, Tingyuan.,Wang, Qibao.,Zhang, Guifeng.,Huo, Junsheng.,...&Wang, Lianyan.(2016).Fabrication of uniform alginate-agarose microcapsules loading FeSO4 using water-oil-water-oil multiple emulsions system combined with premix membrane emulsification technique.COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,498(JUNE),128-138.
MLA	Zhang, Bo,et al."Fabrication of uniform alginate-agarose microcapsules loading FeSO4 using water-oil-water-oil multiple emulsions system combined with premix membrane emulsification technique".COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 498.JUNE(2016):128-138.