Biomedical Applications of Advanced Multifunctional Magnetic Nanoparticles

CORC > 上海硅酸盐研究所 > 中国科学院上海硅酸盐研究所 > 结构陶瓷与复合材料工程研究中心 > 期刊论文

	Biomedical Applications of Advanced Multifunctional Magnetic Nanoparticles
	Nguyen Viet Long 1,2,3; Yang, Yong 1; Teranishi, Toshiharu 3; Cao Minh Thi 4; Cao, Yanqin 1; Nogami, Masayuki 5
刊名	JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
	2015-12-01
卷号	15 期号:12 页码:10091-10107
关键词	Fe Nanoparticles Fe Oxide Nanoparticles Au Nanoparticles Ag Nanoparticles Pt Nanoparticles Drug Delivery Hyperthermia Magnetic Resonance Imaging Drug Cancers Tumors Cancer Therapy
英文摘要	In this review, we have presented the latest results and highlights on biomedical applications of a class of noble metal nanoparticles, such as gold, silver and platinum, and a class of magnetic nanoparticles, such as cobalt, nickel and iron. Their most important related compounds are also discussed for biomedical applications for treating various diseases, typically as cancers. At present, both physical and chemical methods have been proved very successful to synthesize, shape, control, and produce metal- and oxide-based homogeneous particle systems, e.g., nanoparticles and microparticles. Therefore, we have mainly focused on functional magnetic nanoparticles for nanomedicine because of their high bioadaptability to the organs inside human body. Here, bio-conjugation techniques are very crucial to link nanoparticles with conventional drugs, nanodrugs, biomolecules or polymers for biomedical applications. Biofunctionalization of engineered nanoparticles for biomedicine is shown respective to in vitro and in vivo analysis protocols that typically include drug delivery, hyperthermia therapy, magnetic resonance imaging (MRI), and recent outstanding progress in sweep imaging technique with Fourier transformation (SWIFT) MRI. The latter can be especially applied using magnetic nanoparticles, such as Co-, Fe-, Ni-based nanoparticles, alpha-Fe2O3, and Fe3O4 oxide nanoparticles for analysis and treatment of malignancies. Therefore, this review focuses on recent results of scientists, and related research on diagnosis and treatment methods of common and dangerous diseases by biomedical engineered nanoparticles. Importantly, nanosysems (nanoparticles) or microsystems (microparticles) or hybrid micronano systems are shortly introduced into nanomedicine. Here, Fe oxide nanoparticles ultimately enable potential and applicable technologies for tumor-targeted imaging and therapy. Finally, we have shown the latest aspects of the most important Fe-based particle systems, such as Fe, alpha-Fe2O3, Fe3O4, Fe-FexOy oxide core-shell nanoparticles, and CoFe2O4-MnFe2O4 core-shell nanoparticles for nanomedicine in the efficient treatment of large tumors at low cost in near future.
WOS标题词	Science & Technology ; Physical Sciences ; Technology
类目[WOS]	Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter
研究领域[WOS]	Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
关键词[WOS]	IRON-OXIDE NANOPARTICLES ; NOBLE-METAL NANOPARTICLES ; ENHANCED RAMAN-SCATTERING ; DRUG-DELIVERY-SYSTEM ; MRI CONTRAST AGENTS ; IN-VIVO ; SILVER NANOPARTICLES ; THERAPEUTIC APPLICATIONS ; BIOLOGICAL APPLICATIONS ; CANCER-TREATMENT
收录类别	SCI
语种	英语
WOS记录号	WOS:000365555000103
内容类型	期刊论文
源URL	[http://ir.sic.ac.cn/handle/331005/8409]
专题	上海硅酸盐研究所_结构陶瓷与复合材料工程研究中心_期刊论文
作者单位	1.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China 2.Posts & Telecommun Inst Technol, Hanoi 100000, Vietnam 3.Kyoto Univ, Inst Chem Res, Uji, Kyoto 6110011, Japan 4.Ho Chi Minh City Univ Technol, Ho Chi Minh City 700000, Vietnam 5.Toyota Phys & Chem Res Inst, Nagakute, Aichi 4801192, Japan
推荐引用方式 GB/T 7714	Nguyen Viet Long,Yang, Yong,Teranishi, Toshiharu,et al. Biomedical Applications of Advanced Multifunctional Magnetic Nanoparticles[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2015,15(12):10091-10107.
APA	Nguyen Viet Long,Yang, Yong,Teranishi, Toshiharu,Cao Minh Thi,Cao, Yanqin,&Nogami, Masayuki.(2015).Biomedical Applications of Advanced Multifunctional Magnetic Nanoparticles.JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,15(12),10091-10107.
MLA	Nguyen Viet Long,et al."Biomedical Applications of Advanced Multifunctional Magnetic Nanoparticles".JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 15.12(2015):10091-10107.