Four new dimeric spiro-azaplilone derivatives cochliodones E-H from the entophytic fungus Chaetomium sp M336
Yu, Fei-Xue1,2,3; Chen, Yao3; Yang, Yin-He4; Zhao, Pei-Ji1,2,4
刊名PHYTOCHEMISTRY LETTERS
2016-06-01
卷号16页码:263-267
关键词Chaetomium sp M336 Chemical constituents Structure identification Cochliodone Antibacterial activities
英文摘要Chaetomium sp. M336 was isolated from Huperzia serrata (Thunb. ex Murray) Trev. and subjected to phytochemical investigation based on its special environment. To understand the secondary metabolites of strain Chaetomium sp. M336, four new dimeric spiro-azaplilone derivatives cochliodones E-H (1-4) were isolated from solid fermentation products of the fungus, which were elucidated by extensive spectroscopic analyses, including 1D- and 2D NMR, and HR-ESI-MS experiments. The antibacterial activities of compounds 1-4 against bacteria were tested in vitro. They exhibited antibacterial activities against Escherichia coli, Staphylococcus aureus, Salmonella typhimurium ATCC 6539 and Enterococcus faecalis with minimum inhibitory concentration (MIC) values of 0.78-100 mu g/mL. (C) 2016 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
类目[WOS]Biochemistry & Molecular Biology ; Plant Sciences
研究领域[WOS]Biochemistry & Molecular Biology ; Plant Sciences
关键词[WOS]HUPERZINE-A ; ENDOPHYTIC FUNGUS ; NATURAL-PRODUCTS ; PLANTS
收录类别SCI
语种英语
WOS记录号WOS:000378027300047
内容类型期刊论文
源URL[http://ir.kib.ac.cn/handle/151853/26286]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Yunnan Univ, Minist Educ, Lab Conservat & Utilizat Bioresource, Kunming 650091, Peoples R China
2.Yunnan Univ, Minist Educ, Key Lab Microbial Resources, Kunming 650091, Peoples R China
3.Kunming Univ Sci & Technol, Fac Med, Kunming 650500, Peoples R China
4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
推荐引用方式
GB/T 7714
Yu, Fei-Xue,Chen, Yao,Yang, Yin-He,et al. Four new dimeric spiro-azaplilone derivatives cochliodones E-H from the entophytic fungus Chaetomium sp M336[J]. PHYTOCHEMISTRY LETTERS,2016,16:263-267.
APA Yu, Fei-Xue,Chen, Yao,Yang, Yin-He,&Zhao, Pei-Ji.(2016).Four new dimeric spiro-azaplilone derivatives cochliodones E-H from the entophytic fungus Chaetomium sp M336.PHYTOCHEMISTRY LETTERS,16,263-267.
MLA Yu, Fei-Xue,et al."Four new dimeric spiro-azaplilone derivatives cochliodones E-H from the entophytic fungus Chaetomium sp M336".PHYTOCHEMISTRY LETTERS 16(2016):263-267.
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