Phomopchalasins A and B, Two Cytochalasans with Polycyclic-Fused Skeletons from the Endophytic Fungus Phomopsis sp shj2

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Phomopchalasins A and B, Two Cytochalasans with Polycyclic-Fused Skeletons from the Endophytic Fungus Phomopsis sp shj2
	Yan, Bing-Chao 1,4; Wang, Wei-Guang 1; Hu, Dong-Bao 3; Sun, Xiang 2; Kong, Ling-Mei 1; Li, Xiao-Nian 1; Du, Xue 1; Luo, Shi-Hong 1; Liu, Yan 1; Li, Yan1
刊名	ORGANIC LETTERS
	2016-03-04
卷号	18 期号:5 页码:1108-1111
英文摘要	Phomopchalasins A (1) and B (2), two novel cytochalasans with unprecedented carbon skeletons, and phomopchalasin C (3), containing a rare hydroperoxyl motif; were obtained from the endophytic fungus Phomopsis sp. shj2, which was first isolated from the Isodon eriocalyx var. laxiflora. Their structures were elucidated by extensive spectroscopic analyses, electronic circular dichroism (ECD) calculation, and X-ray crystallographic analysis. Notably, 1 possessed an unprecedented 5/6/5/8-fused tetracyclic ring system, and 2 featured a novel 5/6/6/7/5-fused pentacyclic skeleton. The cytotoxic, anti-inflammatory, and antimigratory activities of 1-3 were evaluated in vitro.
类目[WOS]	Chemistry, Organic
研究领域[WOS]	Chemistry
关键词[WOS]	CHAETOMIUM-GLOBOSUM ; ASPERGILLUS-FLAVIPES ; CIRCULAR-DICHROISM ; RING-SYSTEM ; CHAETOGLOBOSIN ; METABOLITES
收录类别	SCI
语种	英语
WOS记录号	WOS:000371754000056
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/26012]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Chinese Acad Sci, Inst Microbiol, State Key Lab Mycol, Beijing 100190, Peoples R China 3.Yuxi Normal Univ, Coll Resource & Environm, Yuxi 653100, Yunnan, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Yan, Bing-Chao,Wang, Wei-Guang,Hu, Dong-Bao,et al. Phomopchalasins A and B, Two Cytochalasans with Polycyclic-Fused Skeletons from the Endophytic Fungus Phomopsis sp shj2[J]. ORGANIC LETTERS,2016,18(5):1108-1111.
APA	Yan, Bing-Chao.,Wang, Wei-Guang.,Hu, Dong-Bao.,Sun, Xiang.,Kong, Ling-Mei.,...&Pu, Jian-Xin.(2016).Phomopchalasins A and B, Two Cytochalasans with Polycyclic-Fused Skeletons from the Endophytic Fungus Phomopsis sp shj2.ORGANIC LETTERS,18(5),1108-1111.
MLA	Yan, Bing-Chao,et al."Phomopchalasins A and B, Two Cytochalasans with Polycyclic-Fused Skeletons from the Endophytic Fungus Phomopsis sp shj2".ORGANIC LETTERS 18.5(2016):1108-1111.