Antioxidant Lignans and Neolignans from Acorus tatarinowii

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Antioxidant Lignans and Neolignans from Acorus tatarinowii
	Lu, Yuanyuan 1,2; Xue, Yongbo 1; Chen, Shenjie 1; Zhu, Hucheng 1; Zhang, Jinwen 2; Li, Xiao-Nian 3; Wang, Jianping 1; Liu, JunJun 1; Qi, Changxing 1; Du, Guang 2
刊名	SCIENTIFIC REPORTS
	2016-03-10
卷号	6
英文摘要	Eleven new lignans and neolignans, named acortatarinowins G-N (1-8), including three pairs of enantiomers (1a/1b-3a/3b) and five optically pure lignans and neolignans (4-8), along with five known analogs (9-14), were isolated from the rhizomes of Acorus tatarinowii Schott. Compounds 1-3 were successfully separated by chiral HPLC to afford 1a/1b-3a/3b. The planar structures of 1-8 were elucidated by extensive spectroscopic analyses including HRESIMS and NMR. Their absolute configurations were determined by analyses of single-crystal X-ray diffraction and a modified Mosher's method, assisted by experimental and calculated electronic circular dichroism (ECD) data. Compounds 1a and 1b were rare 7,8'-epoxy-8,7'-oxyneolignane. Compounds 1-8 were evaluated for their antioxidant activities using 2,2-diphenyl-1-picrylhydrazyl (DPPH) reducing antioxidant power assay. Compound 6, exhibiting strong DPPH radical scavenging capacity with IC50 value of 16.4 +/- 0.22 mu g/mL, could interpret the herbal traditional usage.
类目[WOS]	Multidisciplinary Sciences
研究领域[WOS]	Science & Technology - Other Topics
关键词[WOS]	ABSOLUTE-CONFIGURATIONS ; ARYLTETRALONE LIGNANS ; HOLOSTYLIS-RENIFORMIS ; DERIVATIVES ; ENANTIOMERS
收录类别	SCI
语种	英语
WOS记录号	WOS:000371669600001
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/26008]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Huazhong Univ Sci & Technol, Sch Pharm, Tongji Med Coll, Hubei Key Lab Nat Med Chem & Resource Evaluat, Wuhan 430030, Hubei Province, Peoples R China 2.Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Wuhan 430030, Hubei Province, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
推荐引用方式 GB/T 7714	Lu, Yuanyuan,Xue, Yongbo,Chen, Shenjie,et al. Antioxidant Lignans and Neolignans from Acorus tatarinowii[J]. SCIENTIFIC REPORTS,2016,6.
APA	Lu, Yuanyuan.,Xue, Yongbo.,Chen, Shenjie.,Zhu, Hucheng.,Zhang, Jinwen.,...&Zhang, Yonghui.(2016).Antioxidant Lignans and Neolignans from Acorus tatarinowii.SCIENTIFIC REPORTS,6.
MLA	Lu, Yuanyuan,et al."Antioxidant Lignans and Neolignans from Acorus tatarinowii".SCIENTIFIC REPORTS 6(2016).