Determination of Morphine in Pharmaceutical Products by On-Line Solid-Phase Extraction and High-Performance Liquid Chromatography

CORC > 武汉物理与数学研究所 > 中国科学院武汉物理与数学研究所 > 磁共振基础研究部

	Determination of Morphine in Pharmaceutical Products by On-Line Solid-Phase Extraction and High-Performance Liquid Chromatography
	Yang, Yan-Ling 1; Ye, Xiao-Xue 2; Li, Yu-Sang 1; Tan, Zhi-Fang 3; Jiang, Ji-Zhou 4
刊名	ANALYTICAL LETTERS
	2016
卷号	49 期号:9 页码:1303-1309
关键词	Double-ternary gradient high-performance liquid chromatography morphine traditional Chinese medicine solid-phase extraction
英文摘要	A method for the rapid determination of morphine in Chinese medicines was developed using on-line solid-phase extraction combined with double-ternary gradient liquid chromatography. Licorice tablets and camphor tincture were used as representative examples of traditional Chinese medicine. The results indicated that morphine provided a linear response from 0.0239 to 0.239m g mL(-1). The average recovery was as high as 99% with a relative standard deviation of 0.9%. Moreover, compared with conventional off-line solid-phase extraction and liquid chromatography, this approach offered a significant reduction in the analysis time. This method may provide for more efficient determination of morphine in traditional Chinese medicine.
WOS标题词	Science & Technology ; Physical Sciences
类目[WOS]	Chemistry, Analytical
研究领域[WOS]	Chemistry
关键词[WOS]	COMPOUND LICORICE TABLETS ; GLASSY-CARBON ELECTRODE ; ACID CATALYSTS ; P-31 NMR ; MORPHINE-6-GLUCURONIDE ; MORPHINE-3-GLUCURONIDE ; CODEINE ; PAIN ; MS
收录类别	SCI
语种	英语
WOS记录号	WOS:000375911400001
内容类型	期刊论文
源URL	[http://ir.wipm.ac.cn/handle/112942/9338]
专题	武汉物理与数学研究所_磁共振基础研究部
作者单位	1.South Cent Univ Nationalities, Coll Pharm, Wuhan 430074, Hubei Province, Peoples R China 2.South Cent Univ Nationalities, Coll Chem & Mat Sci, Wuhan 430074, Hubei Province, Peoples R China 3.Chinese Acad Sci, Wuhan Inst Phys & Math, Wuhan, Peoples R China 4.Huazhong Univ Sci & Technol, Coll Chem & Chem Engn, Wuhan 430074, Hubei Province, Peoples R China
推荐引用方式 GB/T 7714	Yang, Yan-Ling,Ye, Xiao-Xue,Li, Yu-Sang,et al. Determination of Morphine in Pharmaceutical Products by On-Line Solid-Phase Extraction and High-Performance Liquid Chromatography[J]. ANALYTICAL LETTERS,2016,49(9):1303-1309.
APA	Yang, Yan-Ling,Ye, Xiao-Xue,Li, Yu-Sang,Tan, Zhi-Fang,&Jiang, Ji-Zhou.(2016).Determination of Morphine in Pharmaceutical Products by On-Line Solid-Phase Extraction and High-Performance Liquid Chromatography.ANALYTICAL LETTERS,49(9),1303-1309.
MLA	Yang, Yan-Ling,et al."Determination of Morphine in Pharmaceutical Products by On-Line Solid-Phase Extraction and High-Performance Liquid Chromatography".ANALYTICAL LETTERS 49.9(2016):1303-1309.