The strong MRI relaxivity of paramagnetic nanoparticles

	The strong MRI relaxivity of paramagnetic nanoparticles
	Xing GM(邢更妹); Yuan H(袁慧); He R(何睿); Gao XY(高学云); Jing L(荆隆); Zhao F(赵峰); Chai ZF(柴之芳); Zhao YL(赵宇亮); Xing, GM; Yuan, H
刊名	JOURNAL OF PHYSICAL CHEMISTRY B
	2008
卷号	112 期号:20 页码:6288-6291
通讯作者	[Xing, Gengmei ; Yuan, Hui ; He, Rui ; Gao, Xueyun ; Jing, Long ; Zhao, Feng ; Chai, Zhifang] Chinese Acad Sci, Lab Bioenvironm Effects Nanomat & Nanosafety, Inst High Energy Phys, Beijing 100049, Peoples R China ; [Zhao, Yuliang] Natl Ctr Nanosci & Technol, Beijing 100080, Peoples R China
英文摘要	We developed a method to synthesize paramagnetic nanoparticles of Gd@C-82(OH)(22 +/- 2). Such nanoparticles are with ordered microstructures and have strong MRI proton relaxation in vitro/vivo. Compared with commercial Gd-DTPA, a 12 x MRI relaxivity of Gd@C-82(OH)(22 +/- 2) nanoparticles with ordered microstructures was achieved in vitro. The small Gd@C-82(OH)(22 +/- 2) nanoparticles, similar to 65nm, could easily escape the RES uptake in vivo; this opens the door for their clinical applications.
学科主题	Chemistry
类目[WOS]	Chemistry, Physical
研究领域[WOS]	Chemistry
原文出处	SCI
语种	英语
WOS记录号	WOS:000255905200002
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/240069]
专题	高能物理研究所_院士高能物理研究所_多学科研究中心
作者单位	中国科学院高能物理研究所
推荐引用方式 GB/T 7714	Xing GM,Yuan H,He R,et al. The strong MRI relaxivity of paramagnetic nanoparticles[J]. JOURNAL OF PHYSICAL CHEMISTRY B,2008,112(20):6288-6291.
APA	邢更妹.,袁慧.,何睿.,高学云.,荆隆.,...&Zhao, YL.(2008).The strong MRI relaxivity of paramagnetic nanoparticles.JOURNAL OF PHYSICAL CHEMISTRY B,112(20),6288-6291.
MLA	邢更妹,et al."The strong MRI relaxivity of paramagnetic nanoparticles".JOURNAL OF PHYSICAL CHEMISTRY B 112.20(2008):6288-6291.