Reliable screening of pesticide residues in maternal and umbilical cord sera by gas chromatography-quadrupole time of flight mass spectrometry

CORC > 上海有机化学研究所 > 中国科学院上海有机化学研究所 > 分析化学研究室

	Reliable screening of pesticide residues in maternal and umbilical cord sera by gas chromatography-quadrupole time of flight mass spectrometry
	Fan RJ(范若静); Zhang F(张芳); Wang HY(王昊阳); Zhang L(张立); Zhang J(张菁); Zhang Y(张莹); Yu CT(余翀天); Guo YL(郭寅龙)
刊名	Sci. China-Chem.
	2014
卷号	57 期号:5 页码:669-677
其他题名	利用GC-QTOF MS对母婴血清中农药残留的筛查
通讯作者	郭寅龙
英文摘要	The widespread use of pesticides induces heavy adverse effects on human health, especially for the pregnant women and the newborns. In this study, a screening method has been developed for the determination of multi-pesticides in maternal and umbilical cord sera. All pesticides in sera were collected using solid phase extraction (SPE), and analyzed by gas chromatography-quadrupole time of flight mass spectrometry (GC-QTOF MS). To set up the quality criteria, a database of 50 pesticides was created and the accurate masses of 3 up to 5 representative ions with their intensity ratios were included for each pesticide. In addition, a novel "identification points" (IPs) system relying on the accurate MS1 and MS2 spectra was used to interpret the data for each suspected pesticide. The methodology was then applied to a pair of maternal and umbilical cord sera. A total of six pesticide residues were screened out successfully. In conclusion, GC-QTOF MS combined with an accurate mass database seemed to be one of the most efficient tools for systematic pesticide analysis.
学科主题	分析化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1007/s11426-013-5023-5
语种	英语
公开日期	2016-05-24
内容类型	期刊论文
源URL	[http://ir.sioc.ac.cn/handle/331003/38583]
专题	上海有机化学研究所_分析化学研究室
作者单位	中科院上海有机化学研究所
推荐引用方式 GB/T 7714	Fan RJ,Zhang F,Wang HY,et al. Reliable screening of pesticide residues in maternal and umbilical cord sera by gas chromatography-quadrupole time of flight mass spectrometry[J]. Sci. China-Chem.,2014,57(5):669-677.
APA	范若静.,张芳.,王昊阳.,张立.,张菁.,...&郭寅龙.(2014).Reliable screening of pesticide residues in maternal and umbilical cord sera by gas chromatography-quadrupole time of flight mass spectrometry.Sci. China-Chem.,57(5),669-677.
MLA	范若静,et al."Reliable screening of pesticide residues in maternal and umbilical cord sera by gas chromatography-quadrupole time of flight mass spectrometry".Sci. China-Chem. 57.5(2014):669-677.